QuickView for DASs (gene)

Gene Symbol:

LTBP3 Homo sapiens

Full name:

latent transforming growth factor beta binding protein 3

Synonyms:

DASS, GPHYSD3, LTBP-3, LTBP2, STHAG6, pp6425, latent-transforming growth factor beta-binding protein 3, latent TGF beta binding protein 3

Genomic Location:

Chr 11: 65062850-65082006

Description:

The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding diff...

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The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PR_Q2 ,  AP1_C ,  TGANTCA_AP1_C ,  RYTTCCTG_ETS2_B ,  AML_Q6 ,  ARP1_01 ,  AP1_Q6 ,  GR_Q6_01 ,  TGACCTY_ERR1_Q2 ,  CAGGTG_E12_Q6 ,  AP1FJ_Q2 ,  NKX62_Q2 ,  AP1_Q2_01 ,  AP1_Q4 ,  RNGTGGGC_UNKNOWN ,  CHX10_01 ,  TAATTA_CHX10_01 ,  AP2REP_01 ,  AP1_Q2 ,  CTTTGT_LEF1_Q2 ,  AP1_Q4_01 ,  CP2_01

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Cytogenetic Map:

11q13.1

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