QuickView for DBI (gene)
- Gene Symbol:
- DBI
Homo sapiens - Full name:
- diazepam binding inhibitor, acyl-CoA binding protein
- Synonyms:
- ACBD1, ACBP, CCK-RP, EP, acyl-CoA-binding protein, GABA receptor modulator, acyl coenzyme A binding protein, acyl-Coenzyme A binding domain containing 1, cholecystokinin-releasing peptide, trypsin-sensitive, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein), diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein), diazepam-binding inhibitor, endozepine
- Genomic Location:
- Chr 2: 119840974-119846592
- Description:
-
This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
2q14.2
GO Molecular Function
cofactor binding | ribonucleotide binding | lipid binding | fatty-acyl-CoA binding | nucleotide binding | coenzyme binding | signaling receptor binding | carbohydrate derivative binding | long-chain fatty acyl-CoA binding | anion binding | adenyl nucleotide binding | amide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | protein binding | benzodiazepine receptor binding | protein dimerization activity | purine ribonucleotide binding | adenyl ribonucleotide binding | heterocyclic compound binding | small molecule binding
GO Biological Process
purine ribonucleotide metabolic process | sulfur compound metabolic process | phospholipid metabolic process | protein palmitoylation | cellular process | phosphatidylcholine acyl-chain remodeling | nucleotide metabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | protein lipidation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | purine nucleotide metabolic process | lipoprotein biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | nitrogen compound metabolic process | phosphorus metabolic process | acyl-CoA metabolic process | lipid metabolic process | organophosphate metabolic process | small molecule metabolic process | cellular amide metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | phosphate-containing compound metabolic process | lipoprotein metabolic process | glycerolipid metabolic process | protein metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | phosphatidylcholine metabolic process | cellular protein metabolic process | cellular macromolecule biosynthetic process | glycerophospholipid metabolic process | cellular protein modification process | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | endomembrane system | vesicle | endoplasmic reticulum lumen | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | membrane-enclosed lumen | intracellular
