QuickView for DEFB114;jsessionid=4130F6FB15BF85DFA5BC4B05B66D8989 (gene)
- Gene Symbol:
- DEFB114
Homo sapiens - Full name:
- defensin beta 114
- Synonyms:
- DEFB-14, DEFB14, beta-defensin 114, beta-defensin 14, defensin, beta 14
- Genomic Location:
- Chr 6: 50035964-50039777
- Description:
-
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded...
- Orthologs:
- Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
6p12.3
GO Molecular Function
lipid binding | carbohydrate derivative binding | lipopolysaccharide binding
GO Biological Process
negative regulation of phosphorylation | negative regulation of MAPK cascade | negative regulation of peptide secretion | regulation of localization | defense response to other organism | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | defense response | negative regulation of protein phosphorylation | negative regulation of protein secretion | defense response to Gram-negative bacterium | negative regulation of signaling | negative regulation of secretion | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | negative regulation of cytokine secretion | negative regulation of tumor necrosis factor production | regulation of peptide secretion | response to stimulus | defense response to fungus | negative regulation of protein transport | response to stress | negative regulation of tumor necrosis factor superfamily cytokine production | negative regulation of protein kinase activity | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | regulation of peptide transport | response to external biotic stimulus | negative regulation of tumor necrosis factor secretion | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | positive regulation of inflammatory response | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | negative regulation of cytokine production | regulation of nitrogen compound metabolic process | negative regulation of protein serine/threonine kinase activity | regulation of cellular protein metabolic process | regulation of tumor necrosis factor production | response to bacterium | response to fungus | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | defense response to bacterium | regulation of protein phosphorylation | negative regulation of MAP kinase activity | regulation of cytokine secretion | regulation of establishment of protein localization | regulation of kinase activity | regulation of lipopolysaccharide-mediated signaling pathway | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | regulation of secretion | immune response | negative regulation of cellular protein metabolic process | regulation of protein secretion | regulation of tumor necrosis factor secretion | antifungal innate immune response | regulation of phosphate metabolic process | negative regulation of protein metabolic process | defense response to Gram-positive bacterium | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of cytokine production | response to biotic stimulus | regulation of transport | innate immune response | immune system process | negative regulation of lipopolysaccharide-mediated signaling pathway | regulation of protein localization | regulation of inflammatory response | response to other organism | regulation of signaling | regulation of phosphorus metabolic process
