QuickView for DGKD;jsessionid=CFF4E6AFAB29FB0A301748A346B65437 (gene)
- Gene Symbol:
- DGKD
Homo sapiens - Full name:
- diacylglycerol kinase delta
- Synonyms:
- DGKdelta, dgkd-2, diacylglycerol kinase delta, DAG kinase delta, DGK-delta, diacylglycerol kinase, delta 130kDa, diglyceride kinase delta
- Genomic Location:
- Chr 2: 233927892-234045482
- Description:
-
This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transdu...
- Orthologs:
- Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
2q37.1
GO Molecular Function
cation binding | ribonucleotide binding | lipid binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | diacylglycerol kinase activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | diacylglycerol binding | phosphotransferase activity, alcohol group as acceptor | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | NAD+ kinase activity | small molecule binding
GO Biological Process
protein homooligomerization | intracellular signal transduction | establishment of localization | cellular process | localization | protein transport | macromolecule localization | hemostasis | regulation of cellular process | epidermal growth factor receptor signaling pathway | cellular component organization | cellular lipid metabolic process | response to stimulus | response to stress | ERBB signaling pathway | G-protein coupled receptor signaling pathway | cellular component assembly | blood coagulation | multicellular organism development | phosphorus metabolic process | protein complex oligomerization | lipid metabolic process | wound healing | platelet activation | organic substance transport | enzyme linked receptor protein signaling pathway | peptide transport | vesicle-mediated transport | second-messenger-mediated signaling | phosphorylation | phosphate-containing compound metabolic process | lipid phosphorylation | cell communication | lipid modification | protein kinase C-activating G-protein coupled receptor signaling pathway | glycerolipid metabolic process | coagulation | protein-containing complex assembly | diacylglycerol metabolic process | response to organic substance | neutral lipid metabolic process | response to wounding | import into cell | diacylglycerol kinase activity | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of body fluid levels | amide transport | endocytosis | organic substance metabolic process | establishment of protein localization | cell activation | signaling | protein localization | kinase activity | developmental process | transmembrane receptor protein tyrosine kinase signaling pathway | cellular metabolic process | acylglycerol metabolic process | NAD+ kinase activity | signal transduction | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | intracellular | membrane
