QuickView for DGKQ;jsessionid=E3E48764583BF66EC571F64EF35E993E (gene)
- Gene Symbol:
- DGKQ
Homo sapiens - Full name:
- diacylglycerol kinase theta
- Synonyms:
- DAGK, DAGK4, DAGK7, diacylglycerol kinase theta, DAG kinase theta, DGK-theta, diacylglycerol kinase, theta 110kDa, diglyceride kinase theta, testis tissue sperm-binding protein Li 38a
- Genomic Location:
- Chr 4: 942675-957344
- Description:
-
The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transducti...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
4p16.3
| Transcripts Names |
|---|
| NM_001347 |
| XM_011513415 |
| XM_011513411 |
| XM_011513412 |
| XM_011513414 |
| XM_017007815 |
| XM_017007814 |
| XR_002959715 |
GO Molecular Function
protein kinase activator activity | kinase binding | enzyme activator activity | protein kinase regulator activity | cation binding | kinase regulator activity | enzyme binding | ribonucleotide binding | nucleotide binding | protein tyrosine kinase activator activity | carbohydrate derivative binding | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | receptor regulator activity | transcription factor binding | diacylglycerol kinase activity | activating transcription factor binding | kinase activator activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | transferase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | phospholipase binding | metal ion binding | heterocyclic compound binding | transmembrane receptor protein tyrosine kinase activator activity | NAD+ kinase activity | receptor activator activity | small molecule binding
GO Biological Process
response to extracellular stimulus | negative regulation of phosphorylation | protein kinase activator activity | response to nutrient levels | response to ATP | intracellular signal transduction | enzyme activator activity | protein kinase regulator activity | regulation of carbohydrate metabolic process | positive regulation of peptidyl-tyrosine phosphorylation | peptidyl-amino acid modification | negative regulation of cellular process | positive regulation of signaling receptor activity | response to drug | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | phospholipid metabolic process | response to organophosphorus | cellular process | regulation of steroid hormone biosynthetic process | kinase regulator activity | positive regulation of protein kinase activity | hemostasis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | cellular lipid metabolic process | response to stimulus | negative regulation of peptidyl-threonine phosphorylation | regulation of peptidyl-tyrosine phosphorylation | activation of transmembrane receptor protein tyrosine kinase activity | positive regulation of protein metabolic process | response to stress | protein tyrosine kinase activator activity | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | cellular component assembly | protein modification process | regulation of steroid biosynthetic process | cellular biosynthetic process | macromolecule modification | regulation of steroid metabolic process | regulation of TOR signaling | activation of protein kinase activity | molecular function regulator | blood coagulation | regulation of nucleic acid-templated transcription | response to nitrogen compound | regulation of protein tyrosine kinase activity | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | phosphatidic acid metabolic process | phosphorus metabolic process | response to purine-containing compound | regulation of progesterone biosynthetic process | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | regulation of hormone levels | wound healing | regulation of gene expression | platelet activation | regulation of TORC1 signaling | protein kinase C signaling | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of ketone biosynthetic process | phospholipid biosynthetic process | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | regulation of transcription by RNA polymerase II | response to nutrient | second-messenger-mediated signaling | regulation of cholesterol metabolic process | biosynthetic process | regulation of hormone metabolic process | regulation of cellular protein metabolic process | phosphorylation | lipid biosynthetic process | cellular protein-containing complex assembly | protein phosphorylation | phosphate-containing compound metabolic process | lipid phosphorylation | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | lipid modification | regulation of protein phosphorylation | protein kinase C-activating G-protein coupled receptor signaling pathway | glycerolipid metabolic process | regulation of RNA metabolic process | regulation of lipid biosynthetic process | coagulation | positive regulation of molecular function | regulation of signaling receptor activity | receptor regulator activity | protein-containing complex assembly | diacylglycerol metabolic process | protein metabolic process | regulation of glucocorticoid biosynthetic process | positive regulation of protein modification process | response to organic substance | neutral lipid metabolic process | glycerophospholipid biosynthetic process | cAMP-mediated signaling | regulation of kinase activity | response to wounding | diacylglycerol kinase activity | regulation of intracellular signal transduction | kinase activator activity | cell surface receptor signaling pathway | regulation of glucose metabolic process | metabolic process | regulation of RNA biosynthetic process | regulation of body fluid levels | organic substance metabolic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | positive regulation of kinase activity | thrombin-activated receptor signaling pathway | regulation of phosphate metabolic process | response to cAMP | cell activation | negative regulation of protein metabolic process | regulation of cell communication | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | cellular protein metabolic process | enzyme regulator activity | regulation of cortisol biosynthetic process | regulation of cellular ketone metabolic process | glycerophospholipid metabolic process | regulation of G-protein coupled receptor protein signaling pathway | kinase activity | peptidyl-serine phosphorylation | cellular protein modification process | response to organonitrogen compound | regulation of gluconeogenesis | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of lipid metabolic process | positive regulation of metabolic process | phosphatidic acid biosynthetic process | cellular metabolic process | regulation of glucocorticoid metabolic process | transmembrane receptor protein tyrosine kinase activator activity | acylglycerol metabolic process | NAD+ kinase activity | receptor activator activity | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of hormone biosynthetic process | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | endomembrane system | nucleoplasm | plasma membrane | nuclear speck | vesicle | endosome | membrane-bounded organelle | nucleus | organelle | vesicle membrane | cell periphery | membrane-enclosed lumen | nuclear matrix | cytosol | intracellular vesicle | cytoskeleton | intracellular | membrane | nuclear periphery
