QuickView for DHX35;jsessionid=377DCE537D9D8C5FDE19251AA59471FB (gene)

Gene Symbol:

DHX35 Homo sapiens

Full name:

DEAH-box helicase 35

Synonyms:

C20orf15, DDX35, KAIA0875, probable ATP-dependent RNA helicase DHX35, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 35, DEAH (Asp-Glu-Ala-His) box polypeptide 35, DEAH-box protein 35

Genomic Location:

Chr 20: 37024414-37101778

Description:

DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patter...

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DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of this gene product which is a member of this family, has not been determined. Alternatively spliced transcript variants have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACGTG_MYC_Q2 ,  MAX_01 ,  GCCATNTTG_YY1_Q6 ,  TGACCTY_ERR1_Q2 ,  GCTTGAA_MIR498 ,  GGGYGTGNY_UNKNOWN ,  USF_01 ,  RNGTGGGC_UNKNOWN ,  T3R_Q6 ,  USF_02

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-378

Cytogenetic Map:

20q11.23-q12

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