QuickView for DIDO1;jsessionid=098A2AD3687F3A1F0E9E1A54AD03E235 (gene)

Gene Symbol:

DIDO1 Homo sapiens

Full name:

death inducer-obliterator 1

Synonyms:

BYE1, C20orf158, DATF-1, DATF1, DIDO2, DIDO3, DIO-1, DIO1, dJ885L7.8, death-inducer obliterator 1, death-associated transcription factor 1

Genomic Location:

Chr 20: 60979535-61039719

Description:

Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal a...

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Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  AGCYRWTTC_UNKNOWN ,  CCCAGAG_MIR326 ,  CTTTAAR_UNKNOWN ,  AAAYRNCTG_UNKNOWN ,  RCGCANGCGY_NRF1_Q6

Cytogenetic Map:

20q13.33

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