QuickView for DNAH8 (gene)
- Gene Symbol:
- DNAH8
Homo sapiens - Full name:
- dynein axonemal heavy chain 8
- Synonyms:
- ATPase, hdhc9, dynein heavy chain 8, axonemal, axonemal beta dynein heavy chain 8, ciliary dynein heavy chain 8, dynein, axonemal, heavy polypeptide 8
- Genomic Location:
- Chr 6: 38798530-39106545
- Description:
-
The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Bos taurus , D. melanogaster , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
6p21.2
GO Molecular Function
dynein light intermediate chain binding | ribonucleotide binding | nucleotide binding | microtubule motor activity | hydrolase activity | carbohydrate derivative binding | dynein intermediate chain binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | motor activity | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ATP-dependent microtubule motor activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | dynein light chain binding | ATP-dependent microtubule motor activity, minus-end-directed | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
axoneme assembly | cell motility | microtubule bundle formation | microtubule cytoskeleton organization | microtubule-based process | cellular process | localization | cellular component organization | axonemal dynein complex assembly | microtubule-based movement | cellular component assembly | locomotion | organelle assembly | outer dynein arm assembly | cell projection assembly | cellular protein-containing complex assembly | cilium or flagellum-dependent cell motility | protein-containing complex assembly | cell projection organization | cilium assembly | cytoskeleton organization | cilium organization | cilium-dependent cell motility | organelle organization
GO Cellular Component
supramolecular fiber | catalytic complex | microtubule associated complex | axonemal dynein complex | dynein complex | cell | microtubule | cytoplasm | intracellular organelle | protein-containing complex | cell projection | plasma membrane bounded cell projection cytoplasm | cilium | microtubule cytoskeleton | cytoplasmic region | outer dynein arm | axoneme | organelle | ciliary plasm | cytoskeleton | intracellular | supramolecular complex
