QuickView for DNAJB5;jsessionid=4BF39E7C5BE812240FC7064240DE1F7D (gene)

Gene Symbol:

DNAJB5 Homo sapiens

Full name:

DnaJ heat shock protein family (Hsp40) member B5

Synonyms:

Hsc40, dnaJ homolog subfamily B member 5, DnaJ (Hsp40) homolog, subfamily B, member 5, heat shock cognate 40, heat shock protein Hsp40-2, heat shock protein Hsp40-3, heat shock protein cognate 40

Genomic Location:

Chr 9: 34979785-34988428

Description:

This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone dea...

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This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  GATTGGY_NFY_Q6_01 ,  GTATTAT_MIR3693P ,  TGIF_01 ,  CREB_Q4_01 ,  ZIC1_01 ,  AREB6_02 ,  P53_DECAMER_Q2 ,  CACGTG_MYC_Q2 ,  TTCNRGNNNNTTC_HSF_Q6 ,  AAANWWTGC_UNKNOWN ,  MAX_01 ,  CTTTGA_LEF1_Q2 ,  E2A_Q2 ,  GGGAGGRR_MAZ_Q6 ,  RGAANNTTC_HSF1_01 ,  CAGGTA_AREB6_01 ,  YYCATTCAWW_UNKNOWN ,  P53_02 ,  CAGGTG_E12_Q6 ,  CTCAGGG_MIR125B_MIR125A ,  HSF1_01 ,  TTCYRGAA_UNKNOWN ,  AP4_01 ,  AP1FJ_Q2 ,  EGR_Q6 ,  GAGCTGG_MIR337 ,  SP3_Q3 ,  ZID_01 ,  MYCMAX_01 ,  ATF3_Q6 ,  GGGCGGR_SP1_Q6 ,  E47_01 ,  GCM_Q2 ,  HSF_Q6 ,  MEIS1_01 ,  HSF2_01 ,  GATA2_01 ,  RNGTGGGC_UNKNOWN ,  GGCAGCT_MIR22 ,  SCGGAAGY_ELK1_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CCAGGGG_MIR331 ,  SREBP_Q3 ,  ZIC2_01 ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  EGR1_01 ,  CAGCTG_AP4_Q5 ,  MMEF2_Q6 ,  TCCCCAC_MIR491 ,  USF_02 ,  GGARNTKYCCA_UNKNOWN ,  NFKB_Q6 ,  PAX4_01 ,  CACTTTG_MIR520G_MIR520H ,  CCTNTMAGA_UNKNOWN ,  ACACTGG_MIR199A_MIR199B

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-199 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-22 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-331 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-491 ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

9p13.3

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