QuickView for DNAJC24;jsessionid=B42CD113FE0C5A9807665EA5CF7D3262 (gene)
- Gene Symbol:
- DNAJC24
Homo sapiens - Full name:
- DnaJ heat shock protein family (Hsp40) member C24
- Synonyms:
- DPH4, JJJ3, ZCSL3, dnaJ homolog subfamily C member 24, 1700030A21Rik, CSL-type zinc finger-containing protein 3, DPH4 homolog (JJJ3, S. cerevisiae), DPH4, JJJ3 homolog, DnaJ (Hsp40) homolog, subfamily C, member 24, diphthamide biosynthesis protein 4, zinc finger, CSL domain containing 3, zinc finger, CSL-type containing 3
- Genomic Location:
- Chr 11: 31347953-31410958
- Description:
-
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involve...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
11p13
GO Molecular Function
enzyme activator activity | cation binding | ferrous iron binding | iron ion binding | molecular function regulator | ion binding | ATPase activator activity | zinc ion binding | transition metal ion binding | enzyme regulator activity | ATPase regulator activity | metal ion binding
GO Biological Process
positive regulation of ATPase activity | enzyme activator activity | peptidyl-amino acid modification | cellular process | chaperone-mediated protein folding | positive regulation of catalytic activity | regulation of cellular process | regulation of metabolic process | regulation of translational elongation | regulation of ATPase activity | posttranscriptional regulation of gene expression | protein modification process | cellular biosynthetic process | macromolecule modification | molecular function regulator | nitrogen compound metabolic process | regulation of catalytic activity | regulation of gene expression | regulation of nitrogen compound metabolic process | positive regulation of hydrolase activity | biosynthetic process | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of molecular function | ATPase activator activity | protein metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | protein folding | regulation of cytoplasmic translation | cellular protein metabolic process | enzyme regulator activity | peptidyl-diphthamide biosynthetic process from peptidyl-histidine | cellular protein modification process | ATPase regulator activity | cellular metabolic process | regulation of translation | macromolecule metabolic process
GO Cellular Component
cell | cytoplasm | intracellular organelle | organelle | cytoskeleton | intracellular
