QuickView for DNM1;jsessionid=63692C0B8DCB83ACAD24320CB008F6CB (gene)

Gene Symbol:

DNM1 Homo sapiens

Full name:

dynamin 1

Synonyms:

DNM, EIEE31, dynamin-1

Genomic Location:

Chr 9: 130005484-130057348

Description:

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded p...

View Full Description

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTANTCA_UNKNOWN ,  TCANNTGAY_SREBP1_01 ,  GTGACTT_MIR224 ,  TGACCTY_ERR1_Q2 ,  GGATTA_PITX2_Q2 ,  AP1FJ_Q2 ,  TGCGCANK_UNKNOWN ,  AP1_Q4 ,  MTF1_Q4 ,  GATGKMRGCG_UNKNOWN ,  GTGGTGA_MIR197 ,  CTGCAGY_UNKNOWN ,  AP1_Q2 ,  PAX4_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-224

Cytogenetic Map:

9q34.11

search → result