QuickView for DOCK10 (gene)

Gene Symbol:

DOCK10 Homo sapiens

Full name:

dedicator of cytokinesis 10

Synonyms:

DRIP2, Nbla10300, ZIZ3, dedicator of cytokinesis protein 10, dopamine receptor interacting protein 2, zizimin3

Genomic Location:

Chr 2: 225338051-225615574

Description:

This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology...

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This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGCAG_MIR518A2 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

2q36.2

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