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QuickView for DRD1 (gene)


Gene Symbol:
DRD1 Homo sapiens Homo sapiens
Full name:
dopamine receptor D1
Synonyms:
DADR, DRD1A, D(1A) dopamine receptor, dopamine D1 receptor
Genomic Location:
Chr 5: 174800281-174803769
Description:
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 5
5q35.2


Transcripts Names
NM_000794
Protein Names
Q4QRJ0
P21728
B2RA44



GO Molecular Function

neurotransmitter receptor activity | cation binding | dopamine neurotransmitter receptor activity, coupled via Gs | transmembrane signaling receptor activity | G-protein coupled receptor activity | dopamine binding | signaling receptor activity | ion binding | organic cyclic compound binding | protein binding | dopamine neurotransmitter receptor activity | drug binding | G-protein alpha-subunit binding

GO Biological Process

positive regulation of release of sequestered calcium ion into cytosol | brain development | regulation of blood vessel diameter | response to radiation | positive regulation of locomotion | cell motility | behavioral fear response | regulation of cellular localization | intracellular signal transduction | regulation of localization | catechol-containing compound metabolic process | subpallium development | peptidyl-amino acid modification | hippocampus development | establishment of localization | response to dopamine | astrocyte development | neuron migration | negative regulation of cellular process | histone modification | cell differentiation | defense response | nervous system development | response to drug | cellular chemical homeostasis | neurogenesis | prepulse inhibition | positive regulation of cellular component movement | generation of neurons | intracellular transport | dopamine transport | phenol-containing compound metabolic process | cellular process | regulation of cell motility | localization | cellular homeostasis | chromatin organization | positive regulation of synaptic transmission | protein transport | dopamine neurotransmitter receptor activity, coupled via Gs | forebrain cell migration | negative regulation of signaling | visual learning | chemical synaptic transmission | cerebral cortex GABAergic interneuron differentiation | neuron development | walking behavior | central nervous system neuron differentiation | synapse assembly | habituation | cerebral cortex neuron differentiation | multicellular organismal reproductive process | learning | macromolecule localization | forebrain neuron differentiation | establishment of localization in cell | regulation of cellular process | regulation of metabolic process | gliogenesis | regulation of cytosolic calcium ion concentration | protein import into nucleus | organic cyclic compound metabolic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | smooth muscle contraction | cellular component organization | positive regulation of potassium ion transport | calcium ion homeostasis | head development | conditioned taste aversion | G-protein coupled receptor activity | muscle contraction | associative learning | response to stimulus | maternal behavior | regulation of blood vessel size | response to cocaine | response to stress | intracellular protein transport | positive regulation of cation transmembrane transport | monosaccharide transmembrane transport | regulation of response to drug | multicellular organismal homeostasis | protein localization to nucleus | telencephalon cell migration | peristalsis | reproduction | cellular localization | organic hydroxy compound transport | regulation of neurotransmitter uptake | regulation of dopamine metabolic process | cellular response to organic cyclic compound | blood circulation | G-protein coupled receptor signaling pathway | neuronal action potential | cellular component assembly | protein modification process | modulation of chemical synaptic transmission | positive regulation of synaptic transmission, glutamatergic | macromolecule modification | cell-cell signaling | GABAergic neuron differentiation | synaptic transmission, dopaminergic | dopamine metabolic process | metal ion homeostasis | regulation of catecholamine metabolic process | regulation of membrane potential | regulation of neurotransmitter levels | locomotion | organic hydroxy compound metabolic process | response to nitrogen compound | central nervous system neuron development | regulation of calcium ion transport into cytosol | response to light stimulus | system development | nitrogen compound metabolic process | reproductive process | positive regulation of calcium ion transmembrane transport | multicellular organism development | cell migration | regulation of synaptic transmission, glutamatergic | phosphorus metabolic process | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | histone H3-S10 phosphorylation | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | forebrain neuron development | regulation of phosphorylation | nonassociative learning | cellular response to ammonium ion | telencephalon development | cerebral cortex GABAergic interneuron development | regulation of gene expression | organic substance transport | nervous system process | synaptic signaling | adult walking behavior | cellular ion homeostasis | adult locomotory behavior | regulation of dopamine uptake involved in synaptic transmission | response to ammonium ion | positive regulation of ion transmembrane transport | striatum development | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | peptide transport | hexose transmembrane transport | regulation of cellular component movement | synapse organization | regulation of synaptic transmission, dopaminergic | protein localization to organelle | behavioral response to cocaine | import into nucleus | second-messenger-mediated signaling | cerebral cortex GABAergic interneuron migration | cognition | regulation of release of sequestered calcium ion into cytosol | positive regulation of cell migration | locomotory behavior | regulation of cellular protein metabolic process | glial cell differentiation | phosphorylation | parental behavior | regulation of calcium ion transmembrane transport | startle response | response to toxic substance | response to xenobiotic stimulus | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | protein import | cellular response to drug | dopamine receptor signaling pathway | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | response to catecholamine | astrocyte differentiation | cyclic-nucleotide-mediated signaling | dentate gyrus development | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | limbic system development | regulation of protein phosphorylation | phospholipase C-activating dopamine receptor signaling pathway | regulation of locomotion | histone phosphorylation | regulation of tube size | positive regulation of transport | carbohydrate transport | drug metabolic process | regulation of potassium ion transport | carbohydrate transmembrane transport | long term synaptic depression | neuron differentiation | multicellular organism reproduction | response to monoamine | activation of adenylate cyclase activity | multicellular organismal response to stress | fear response | protein metabolic process | response to organic substance | visual behavior | cAMP-mediated signaling | catecholamine metabolic process | establishment of protein localization to organelle | anatomical structure development | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | response to amine | reproductive behavior | vasodilation | metabolic process | dopamine neurotransmitter receptor activity | mating behavior | regulation of tube diameter | cellular protein localization | glucose import | histone-serine phosphorylation | amide transport | chemical homeostasis | forebrain generation of neurons | behavior | organic substance metabolic process | regulation of sequestering of calcium ion | mating | nuclear transport | grooming behavior | animal organ development | positive regulation of ion transport | forebrain development | pallium development | ion homeostasis | regulation of phosphate metabolic process | response to alkaloid | regulation of ion transmembrane transport | phospholipase C-activating G-protein coupled receptor signaling pathway | establishment of protein localization | temperature homeostasis | drug transport | glucose transmembrane transport | memory | adult behavior | interneuron migration from the subpallium to the cortex | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | interneuron migration | transmembrane transport | action potential | signaling | covalent chromatin modification | feeding behavior | glial cell development | response to organic cyclic compound | neuromuscular process | cell development | protein localization | cellular protein metabolic process | cation transport | cellular macromolecule localization | operant conditioning | positive regulation of calcium ion transport into cytosol | nucleocytoplasmic transport | ammonium transport | regulation of ion transport | developmental process | organelle organization | behavioral defense response | peptidyl-serine phosphorylation | regulation of calcium ion transport | cellular protein modification process | monoamine transport | sensitization | regulation of transport | response to organonitrogen compound | cellular metal ion homeostasis | transmission of nerve impulse | negative regulation of synaptic transmission | cellular response to dopamine | central nervous system development | response to anesthetic | positive regulation of metabolic process | chromosome organization | regulation of synaptic plasticity | response to amphetamine | ion transport | adenylate cyclase-activating dopamine receptor signaling pathway | cellular metabolic process | long-term synaptic potentiation | cellular response to organic substance | positive regulation of cell motility | positive regulation of blood vessel diameter | divalent inorganic cation homeostasis | sexual reproduction | positive regulation of calcium ion transport | muscle system process | positive regulation of signaling | cellular response to catecholamine stimulus | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

non-motile cilium | integral component of membrane | intracellular membrane-bounded organelle | ciliary membrane | organelle membrane | cell projection membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | cell projection | endomembrane system | endoplasmic reticulum membrane | plasma membrane | cilium | integral component of plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane | intrinsic component of plasma membrane