Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for DRD5;jsessionid=851C9E7D347AA3D49E84C243D61FDCA6 (gene)


Gene Symbol:
DRD5 Homo sapiens Homo sapiens
Full name:
dopamine receptor D5
Synonyms:
DBDR, DRD1B, DRD1L2, D(1B) dopamine receptor, D1beta dopamine receptor, d(5) dopamine receptor, dopamine D5 receptor, dopamine receptor D1B
Genomic Location:
Chr 4: 9392701-9394731
Description:
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4p16.1


Transcripts Names
NM_000798
Protein Names
B2R9S3
Q8NEQ8
P21918



GO Molecular Function

neurotransmitter receptor activity | cation binding | dopamine neurotransmitter receptor activity, coupled via Gs | transmembrane signaling receptor activity | G-protein coupled receptor activity | dopamine binding | signaling receptor activity | ion binding | organic cyclic compound binding | protein binding | dopamine neurotransmitter receptor activity | drug binding | G-protein alpha-subunit binding

GO Biological Process

positive regulation of cyclase activity | regulation of blood vessel diameter | regulation of systemic arterial blood pressure by hormone | positive regulation of lyase activity | intracellular signal transduction | negative regulation of cellular process | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | response to drug | reactive oxygen species metabolic process | cellular chemical homeostasis | cellular process | cellular homeostasis | dopamine neurotransmitter receptor activity, coupled via Gs | negative regulation of signaling | chemical synaptic transmission | negative regulation of NAD(P)H oxidase activity | multicellular organismal reproductive process | learning | positive regulation of catalytic activity | regulation of cellular process | regulation of metabolic process | cellular response to organonitrogen compound | regulation of systemic arterial blood pressure mediated by a chemical signal | calcium ion homeostasis | G-protein coupled receptor activity | associative learning | response to stimulus | positive regulation of blood pressure | female mating behavior | regulation of blood vessel size | response to cocaine | response to stress | regulation of female receptivity | reproduction | cellular response to organic cyclic compound | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | modulation of chemical synaptic transmission | cell-cell signaling | synaptic transmission, dopaminergic | metal ion homeostasis | negative regulation of blood pressure | negative regulation of blood vessel diameter | response to nitrogen compound | reproductive process | negative regulation of catalytic activity | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | wound healing | nonassociative learning | nervous system process | regulation of blood pressure | synaptic signaling | regulation of systemic arterial blood pressure | cellular ion homeostasis | response to ammonium ion | second-messenger-mediated signaling | cognition | positive regulation of adenylate cyclase activity | vasoconstriction | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure | response to toxic substance | regulation of cyclase activity | response to xenobiotic stimulus | cation homeostasis | regulation of systemic arterial blood pressure by vasopressin | dopamine receptor signaling pathway | cellular cation homeostasis | endocrine process | cell communication | response to catecholamine | cyclic-nucleotide-mediated signaling | cellular calcium ion homeostasis | homeostatic process | phospholipase C-activating dopamine receptor signaling pathway | regulation of tube size | long term synaptic depression | positive regulation of molecular function | multicellular organism reproduction | response to monoamine | activation of adenylate cyclase activity | response to organic substance | cAMP-mediated signaling | response to wounding | response to amine | reproductive behavior | metabolic process | dopamine neurotransmitter receptor activity | mating behavior | regulation of tube diameter | chemical homeostasis | behavior | mating | ion homeostasis | response to alkaloid | phospholipase C-activating G-protein coupled receptor signaling pathway | regulation of adenylate cyclase activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of molecular function | signaling | regulation of oxidoreductase activity | response to organic cyclic compound | regulation of NAD(P)H oxidase activity | sensitization | negative regulation of oxidoreductase activity | response to organonitrogen compound | cellular metal ion homeostasis | transmission of nerve impulse | negative regulation of synaptic transmission | response to anesthetic | regulation of synaptic plasticity | response to amphetamine | adenylate cyclase-activating dopamine receptor signaling pathway | cellular metabolic process | cellular response to organic substance | divalent inorganic cation homeostasis | sexual reproduction | cellular response to catecholamine stimulus | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

brush border | non-motile cilium | integral component of membrane | ciliary membrane | organelle membrane | cell projection membrane | cell | intrinsic component of membrane | brush border membrane | cell projection | plasma membrane | cilium | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane | intrinsic component of plasma membrane