QuickView for DTL (gene)
- Gene Symbol:
- DTL
Homo sapiens - Full name:
- denticleless E3 ubiquitin protein ligase homolog
- Synonyms:
- CDT2, DCAF2, L2DTL, RAMP, denticleless protein homolog, DDB1- and CUL4-associated factor 2, RA-regulated nuclear matrix-associated protein, lethal(2) denticleless protein homolog, retinoic acid-regulated nuclear matrix-associated protein
- Genomic Location:
- Chr 1: 210275754-210344809
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
1q32.3
GO Molecular Function
catalytic activity | ubiquitin-like protein transferase activity | protein binding | ubiquitin-protein transferase activity | transferase activity
GO Biological Process
response to radiation | regulation of cell cycle process | detection of stimulus | intracellular signal transduction | proteolysis | translesion synthesis | positive regulation of G2/M transition of mitotic cell cycle | negative regulation of cellular process | positive regulation of protein catabolic process | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | postreplication repair | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | positive regulation of cell cycle phase transition | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | response to UV | response to stimulus | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell cycle phase transition | cellular protein catabolic process | cellular nitrogen compound metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | DNA repair | regulation of cell cycle G2/M phase transition | response to light stimulus | nitrogen compound metabolic process | protein monoubiquitination | negative regulation of cell cycle G2/M phase transition | cellular response to DNA damage stimulus | positive regulation of cell cycle | positive regulation of mitotic cell cycle | signal transduction in response to DNA damage | DNA biosynthetic process | cellular response to stress | protein catabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | positive regulation of cell cycle G2/M phase transition | biosynthetic process | aromatic compound biosynthetic process | signal transduction involved in cell cycle checkpoint | cell communication | regulation of protein metabolic process | regulation of mitotic cell cycle | protein polyubiquitination | protein metabolic process | protein ubiquitination | DNA metabolic process | cellular macromolecule catabolic process | positive regulation of mitotic cell cycle phase transition | DNA damage response, detection of DNA damage | metabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | nucleobase-containing compound metabolic process | signal transduction involved in G2 DNA damage checkpoint | organic substance metabolic process | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | negative regulation of cell cycle | organonitrogen compound catabolic process | signaling | cellular protein metabolic process | cellular macromolecule biosynthetic process | signal transduction involved in DNA damage checkpoint | positive regulation of cell cycle process | cellular protein modification process | DNA synthesis involved in DNA repair | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | negative regulation of cell cycle process | modification-dependent protein catabolic process | DNA damage checkpoint | cell cycle checkpoint | DNA replication | signal transduction | post-translational protein modification | macromolecule metabolic process
GO Cellular Component
Cul4B-RING E3 ubiquitin ligase complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | organelle membrane | microtubule organizing center | nuclear membrane | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | ubiquitin ligase complex | centrosome | protein-containing complex | endomembrane system | nucleoplasm | nuclear envelope | transferase complex | microtubule cytoskeleton | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | Cul4-RING E3 ubiquitin ligase complex | Cul4A-RING E3 ubiquitin ligase complex | cytosol | cytoskeleton | intracellular | membrane
