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QuickView for Dcstamp (gene)


Gene Symbol:
DCSTAMP Homo sapiens Homo sapiens
Full name:
dendrocyte expressed seven transmembrane protein
Synonyms:
FIND, TM7SF4, hDC-STAMP, dendritic cell-specific transmembrane protein, DC-specific transmembrane protein, Dendritic cells (DC)-specific transmembrane protein, IL-4-induced protein, IL-Four (IL-4) induced, IL-Four INDuced, IL-four-induced protein, transmembrane 7 superfamily member 4
Genomic Location:
Chr 8: 105421230-105438092
Description:
This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8q22.3





GO Molecular Function

protein binding

GO Biological Process

regulation of monocyte differentiation | response to cytokine | positive regulation of cellular component organization | syncytium formation by plasma membrane fusion | regulation of immune system process | myeloid cell differentiation | negative regulation of cellular process | membrane fusion | positive regulation of developmental process | cellular response to tumor necrosis factor | cell differentiation | membrane organization | regulation of bone remodeling | cellular process | regulation of syncytium formation by plasma membrane fusion | immune system development | myeloid dendritic cell differentiation | regulation of myeloid cell differentiation | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of cellular process | leukocyte activation | cellular component organization | response to stimulus | positive regulation of immune system process | myeloid dendritic cell activation | hemopoiesis | leukocyte differentiation | system development | negative regulation of growth | multicellular organism development | syncytium formation | osteoclast differentiation | myeloid leukocyte differentiation | positive regulation of syncytium formation by plasma membrane fusion | positive regulation of monocyte differentiation | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | cellular response to cytokine stimulus | osteoclast fusion | negative regulation of cell growth | cellular response to interleukin-4 | regulation of growth | response to organic substance | regulation of hemopoiesis | anatomical structure development | multinuclear osteoclast differentiation | dendritic cell differentiation | regulation of bone resorption | regulation of tissue remodeling | animal organ development | cell activation | anatomical structure formation involved in morphogenesis | anatomical structure morphogenesis | positive regulation of tissue remodeling | regulation of developmental process | positive regulation of macrophage fusion | developmental process | regulation of cell growth | positive regulation of bone resorption | cellular response to macrophage colony-stimulating factor stimulus | positive regulation of myeloid leukocyte differentiation | immune system process | hematopoietic or lymphoid organ development | response to tumor necrosis factor | cellular response to organic substance | regulation of cellular component organization | multicellular organismal process | response to interleukin-4

GO Cellular Component

endoplasmic reticulum-Golgi intermediate compartment | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | integral component of endoplasmic reticulum membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | intrinsic component of endoplasmic reticulum membrane | endoplasmic reticulum | endosome membrane | nuclear outer membrane-endoplasmic reticulum membrane network | endoplasmic reticulum-Golgi intermediate compartment membrane | endomembrane system | endoplasmic reticulum membrane | plasma membrane | vesicle | endosome | membrane-bounded organelle | organelle | cell periphery | intracellular vesicle | cell surface | intracellular | membrane