Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for Dihydrolipoamide Dehydrogenase (gene)

Gene Symbol:
DLD Homo sapiens Homo sapiens
Full name:
dihydrolipoamide dehydrogenase
DLDD, DLDH, E3, GCSL, LAD, PHE3, dihydrolipoyl dehydrogenase, mitochondrial, E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex, diaphorase, glycine cleavage system L protein, glycine cleavage system protein L, lipoamide dehydrogenase, lipoamide reductase, lipoyl dehydrogenase
Genomic Location:
Chr 7: 107318822-107348879
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Canis lupus familiaris Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 7

GO Molecular Function

oxidoreductase activity, acting on NAD(P)H | cofactor binding | pyruvate dehydrogenase activity | dihydrolipoyl dehydrogenase activity | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | anion binding | electron transfer activity | oxidoreductase activity, acting on a sulfur group of donors | amide binding | ion binding | organic cyclic compound binding | lipoamide binding | protein binding | NAD binding | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | pyruvate dehydrogenase (NAD+) activity | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | oxidoreductase activity, acting on NAD(P)H | developmental process involved in reproduction | proteolysis | sulfur compound metabolic process | pyruvate dehydrogenase activity | cell differentiation | male gamete generation | acetyl-CoA biosynthetic process | generation of precursor metabolites and energy | dihydrolipoyl dehydrogenase activity | cellular process | cellular homeostasis | dicarboxylic acid metabolic process | cell maturation | nucleotide metabolic process | ATP synthesis coupled electron transport | cellular respiration | multicellular organismal reproductive process | ribose phosphate metabolic process | purine nucleotide biosynthetic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | gamete generation | regulation of cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | purine nucleotide metabolic process | monocarboxylic acid metabolic process | cell redox homeostasis | germ cell development | cellular nitrogen compound biosynthetic process | electron transport chain | acetyl-CoA metabolic process | reproduction | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | spermatid differentiation | protein modification process | cellular biosynthetic process | embryo development | macromolecule modification | nucleotide biosynthetic process | regulation of membrane potential | nitrogen compound metabolic process | reproductive process | coenzyme biosynthetic process | multicellular organism development | phosphorus metabolic process | acyl-CoA metabolic process | lipid metabolic process | electron transfer activity | oxidoreductase activity, acting on a sulfur group of donors | acetyl-CoA biosynthetic process from pyruvate | organophosphate metabolic process | cofactor biosynthetic process | small molecule metabolic process | cellular amide metabolic process | mitochondrial acetyl-CoA biosynthetic process from pyruvate | nucleobase-containing small molecule metabolic process | biosynthetic process | pyruvate metabolic process | aromatic compound biosynthetic process | phosphorylation | purine ribonucleotide biosynthetic process | phosphate-containing compound metabolic process | 2-oxoglutarate metabolic process | mitochondrial ATP synthesis coupled electron transport | homeostatic process | embryonic morphogenesis | drug metabolic process | carboxylic acid metabolic process | multicellular organism reproduction | protein metabolic process | anatomical structure development | metabolic process | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | developmental maturation | oxidation-reduction process | pyruvate dehydrogenase (NAD+) activity | oxidative phosphorylation | nucleobase-containing compound metabolic process | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | organic substance metabolic process | amide biosynthetic process | spermatid development | lipoate metabolic process | fatty acid metabolic process | sperm capacitation | ribose phosphate biosynthetic process | cell development | organic acid metabolic process | cellular protein metabolic process | anatomical structure morphogenesis | energy derivation by oxidation of organic compounds | developmental process | nicotinamide nucleotide metabolic process | spermatogenesis | cellular protein modification process | dihydrolipoamide metabolic process | carbohydrate derivative metabolic process | mitochondrial electron transport, NADH to ubiquinone | heterocycle metabolic process | gastrulation | cellular metabolic process | ATP metabolic process | histone succinylation | oxidoreductase activity | aging | sexual reproduction | macromolecule metabolic process | multicellular organismal process | respiratory electron transport chain

GO Cellular Component

secretory granule | mitochondrial matrix | acrosomal matrix | intracellular membrane-bounded organelle | catalytic complex | cytoplasmic vesicle | cell | oxidoreductase complex | nuclear lumen | pyruvate dehydrogenase complex | cytoplasm | oxoglutarate dehydrogenase complex | acrosomal vesicle | intracellular organelle | motile cilium | protein-containing complex | cell projection | secretory vesicle | endomembrane system | nucleoplasm | cilium | vacuole | vesicle | transferase complex | mitochondrion | membrane-bounded organelle | nucleus | organelle | tricarboxylic acid cycle enzyme complex | membrane-enclosed lumen | intracellular vesicle | intracellular | myelin sheath