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QuickView for Dilp2 (gene)


Gene Symbol:
Flna Mus musculus Mus musculus
Full name:
filamin, alpha
Synonyms:
ABP-280, Dilp2, F730004A14Rik, Fln1, GENA 379, filamin-1, filamin-A, actin-binding protein 280, dilated pupils 2, endothelial actin-binding protein, non-muscle filamin
Genomic Location:
Chr X: 71468800-71491873
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

actin binding | kinase binding | actin filament binding | GTPase binding | Rho GTPase binding | channel regulator activity | opioid receptor binding | protein kinase binding | enzyme binding | protein-containing complex binding | signaling receptor binding | Ral GTPase binding | Ras GTPase binding | molecular function regulator | ion channel binding | protein kinase C binding | cytoskeletal protein binding | identical protein binding | Fc-gamma receptor I complex binding | potassium channel regulator activity | mu-type opioid receptor binding | protein binding | protein homodimerization activity | transcription factor binding | protein dimerization activity | Rac GTPase binding | G-protein coupled receptor binding | immunoglobulin receptor binding | small GTPase binding | SMAD binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | brain development | regulation of supramolecular fiber organization | cell morphogenesis | regulation of muscle system process | positive regulation of locomotion | actin filament-based process | microtubule cytoskeleton organization involved in mitosis | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | developmental process involved in reproduction | protein localization to cell periphery | regulation of cell development | protein stabilization | regulation of localization | morphogenesis of an epithelium | gonad development | regulation of programmed cell death | actin cytoskeleton organization | regulation of transcription by RNA polymerase I | establishment of localization | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | microtubule cytoskeleton organization | cell differentiation | nervous system development | epithelial to mesenchymal transition | neurogenesis | positive regulation of cell adhesion | regulation of organelle organization | positive regulation of cellular component movement | generation of neurons | mesenchyme development | intracellular transport | microtubule-based process | blood vessel morphogenesis | cellular process | channel regulator activity | regulation of neuron migration | regulation of cell motility | localization | regulation of integrin-mediated signaling pathway | tissue remodeling | heart morphogenesis | reproductive system development | negative regulation of nucleic acid-templated transcription | regulation of atrial cardiac muscle cell action potential | macromolecule localization | negative regulation of apoptotic process | Sertoli cell differentiation | regulation of neuron projection development | spindle assembly | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | cytosolic transport | regulation of cell differentiation | actin crosslink formation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | positive regulation of potassium ion transport | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | development of primary sexual characteristics | head development | regulation of atrial cardiac muscle cell membrane repolarization | response to stimulus | vasculature development | wound healing, spreading of cells | blood vessel remodeling | mitotic spindle organization | response to stress | positive regulation of cation transmembrane transport | positive regulation of integrin-mediated signaling pathway | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | negative regulation of neuron projection development | positive regulation of actin filament bundle assembly | tube morphogenesis | regulation of blood circulation | regulation of cardiac muscle cell contraction | epithelial cell development | receptor clustering | supramolecular fiber organization | reproduction | cellular localization | cardiovascular system development | cellular nitrogen compound metabolic process | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | cellular component assembly | formation of radial glial scaffolds | mRNA metabolic process | regulation of cell adhesion | cellular biosynthetic process | molecular function regulator | epiboly | blood vessel development | regulation of nucleic acid-templated transcription | regulation of potassium ion transmembrane transport | regulation of membrane potential | locomotion | organelle assembly | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | regulation of protein stability | regulation of actin cytoskeleton organization | multicellular organism development | cell migration | regulation of actin filament organization | actin filament organization | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of muscle contraction | early endosome to late endosome transport | mRNA transcription by RNA polymerase II | wound healing | localization within membrane | protein localization to plasma membrane | regulation of neuron differentiation | regulation of gene expression | protein localization to membrane | cell cycle | cell projection assembly | animal organ morphogenesis | positive regulation of ion transmembrane transport | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | regulation of membrane repolarization during cardiac muscle cell action potential | cytoplasmic sequestering of protein | negative regulation of DNA-binding transcription factor activity | vesicle-mediated transport | regulation of cellular component movement | morphogenesis of an epithelial sheet | positive regulation of cell differentiation | positive regulation of cell migration | biosynthetic process | aromatic compound biosynthetic process | angiogenesis | hindbrain development | protein localization to cell junction | potassium channel regulator activity | protein localization to cell surface | regulation of heart contraction | cell morphogenesis involved in differentiation | negative regulation of transcription by RNA polymerase I | regulation of striated muscle contraction | maintenance of protein location | dopamine receptor signaling pathway | cell communication | regulation of cellular metabolic process | regulation of cardiac muscle contraction | positive regulation of cytoskeleton organization | regulation of cardiac muscle cell action potential | regulation of protein metabolic process | positive regulation of signal transduction | heart development | positive regulation of cell proliferation | mRNA transcription | regulation of locomotion | regulation of RNA metabolic process | positive regulation of transport | regulation of potassium ion transport | development of primary male sexual characteristics | regulation of cell morphogenesis involved in differentiation | positive regulation of potassium ion transmembrane transport | negative regulation of cell projection organization | tissue morphogenesis | male sex differentiation | response to wounding | regulation of DNA-binding transcription factor activity | Sertoli cell development | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | nuclear division | cell projection organization | metabolic process | positive regulation of cell development | mesenchymal cell differentiation | positive regulation of supramolecular fiber organization | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | male gonad development | cellular protein localization | actin cytoskeleton reorganization | nucleobase-containing compound metabolic process | positive regulation of neuron migration | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | positive regulation of ion transport | negative regulation of neuron differentiation | positive regulation of cell-substrate adhesion | cilium assembly | gene expression | cell migration in hindbrain | cytoskeleton organization | regulation of ion transmembrane transport | mitotic nuclear division | establishment of protein localization | transcription, DNA-templated | anatomical structure formation involved in morphogenesis | cilium organization | negative regulation of protein catabolic process | negative regulation of protein metabolic process | regulation of action potential | establishment of Sertoli cell barrier | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | adenylate cyclase-inhibiting dopamine receptor signaling pathway | regulation of cell communication | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | cell development | protein localization | anatomical structure morphogenesis | cellular macromolecule localization | cellular macromolecule biosynthetic process | regulation of actin filament bundle assembly | reproductive structure development | regulation of nervous system development | regulation of developmental process | regulation of ion transport | positive regulation of neural precursor cell proliferation | developmental process | organelle organization | regulation of cardiac conduction | tube development | regulation of transport | epithelial cell differentiation | heterocycle metabolic process | regulation of membrane repolarization during action potential | regulation of membrane repolarization during atrial cardiac muscle cell action potential | mitotic spindle assembly | central nervous system development | regulation of actin filament-based process | protein localization to bicellular tight junction | regulation of cell projection organization | cellular metabolic process | regulation of cell death | sex differentiation | positive regulation of cell motility | regulation of substrate adhesion-dependent cell spreading | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell death | negative regulation of cell development | circulatory system development | spindle organization | semaphorin-plexin signaling pathway | positive regulation of substrate adhesion-dependent cell spreading | regulation of membrane repolarization | negative regulation of cell differentiation | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | cell-cell junction organization

GO Cellular Component

supramolecular fiber | brush border | chromosome | dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | sarcomere | cell body | cell | nuclear lumen | neuronal cell body | distal axon | nucleolus | myofibril | cytoplasm | cortical cytoskeleton | intracellular organelle | actin cytoskeleton | dendritic tree | contractile fiber | cell-cell junction | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | Myb complex | perinuclear region of cytoplasm | cytoplasmic region | filamentous actin | site of polarized growth | cell cortex | membrane-bounded organelle | dendritic shaft | nucleus | organelle | I band | apical dendrite | cell periphery | axon | membrane-enclosed lumen | trans-Golgi network | growth cone | Z disc | cytosol | actin filament | cytoskeleton | intracellular | cell junction | actin filament bundle | membrane | supramolecular complex