QuickView for Dis3p (gene)
- Gene Symbol:
- DIS3
Homo sapiens - Full name:
- DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
- Synonyms:
- 2810028N01Rik, EXOSC11, KIAA1008, RRP44, dis3p, exosome complex exonuclease RRP44, DIS3 exosome endoribonuclease and 3'-5' exoribonuclease, DIS3 mitotic control homolog, exosome component 11, mitotic control protein dis3 homolog, ribosomal RNA-processing protein 44
- Genomic Location:
- Chr 13: 72227541-72254007
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
13q21.33
GO Molecular Function
guanyl-nucleotide exchange factor activity | nuclease activity | GTPase binding | 3'-5'-exoribonuclease activity | enzyme binding | nucleic acid binding | exoribonuclease activity | hydrolase activity | ribonuclease activity | molecular function regulator | catalytic activity | hydrolase activity, acting on ester bonds | exoribonuclease activity, producing 5'-phosphomonoesters | organic cyclic compound binding | protein binding | 3'-5' exonuclease activity | endonuclease activity | exonuclease activity | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | guanyl-nucleotide exchange factor activity | RNA processing | nuclease activity | 3'-5'-exoribonuclease activity | nuclear-transcribed mRNA catabolic process, exonucleolytic | cellular process | organic substance catabolic process | ribosome biogenesis | regulation of mRNA stability | regulation of cellular process | regulation of metabolic process | catabolic process | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | mRNA catabolic process | exoribonuclease activity | posttranscriptional regulation of gene expression | ncRNA processing | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | negative regulation of metabolic process | CUT catabolic process | mRNA metabolic process | ribonuclease activity | nuclear-transcribed mRNA catabolic process | nucleobase-containing compound catabolic process | molecular function regulator | nitrogen compound metabolic process | regulation of gene expression | RNA catabolic process | regulation of nitrogen compound metabolic process | regulation of RNA stability | exoribonuclease activity, producing 5'-phosphomonoesters | rRNA metabolic process | rRNA catabolic process | regulation of cellular metabolic process | aromatic compound catabolic process | regulation of RNA metabolic process | rRNA processing | cellular macromolecule catabolic process | metabolic process | 3'-5' exonuclease activity | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | regulation of mRNA catabolic process | RNA phosphodiester bond hydrolysis | gene expression | endonuclease activity | RNA phosphodiester bond hydrolysis, exonucleolytic | exonuclease activity | ncRNA metabolic process | heterocycle metabolic process | ribonucleoprotein complex biogenesis | cellular metabolic process | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | exosome (RNase complex) | nuclear exosome (RNase complex) | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoplasmic exosome (RNase complex) | cytosol | intracellular | membrane
