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QuickView for Dlgh2 (gene)


Gene Symbol:
Dlg2 Rattus norvegicus Rattus norvegicus
Full name:
discs large MAGUK scaffold protein 2
Synonyms:
Dlgh2, disks large homolog 2, channel-associated protein of synapse-110, chapsyn-110, discs, large homolog 2, postsynaptic density protein PSD-93, synaptic density protein PSD-93
Genomic Location:
Chr 1: 147878883-149274633
Description:
membrane associated guanylate kinase localized at postsynaptic density (PSD); may function to maintain the structure of PSD by concentrating its components to the membrane area
Orthologs:
Homo sapiens Mus musculus D. melanogaster Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AAANWWTGC_UNKNOWN AP4_01 AACTTT_UNKNOWN ELK1_01 RSRFC4_01 SOX5_01 COMP1_01 GATA1_01 EVI1_04 PBX1_01
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

kinase binding | enzyme binding | signaling receptor binding | protein domain specific binding | protein heterodimerization activity | protein binding | protein phosphatase binding | protein dimerization activity | PDZ domain binding | phosphatase binding | protein C-terminus binding | glutamate receptor binding | ionotropic glutamate receptor binding

GO Biological Process

purine ribonucleotide metabolic process | regulation of dephosphorylation | microtubule-based transport | neuronal ion channel clustering | GMP metabolic process | establishment of localization | negative regulation of cellular process | response to potassium ion | regulation of phosphatase activity | response to metal ion | cell differentiation | nervous system development | neurogenesis | axo-dendritic protein transport | establishment or maintenance of apical/basal cell polarity | generation of neurons | membrane organization | intracellular transport | microtubule-based process | cellular process | localization | cell maturation | anterograde axonal protein transport | protein transport | nucleotide metabolic process | chemical synaptic transmission | neuron development | ribose phosphate metabolic process | cellular response to potassium ion | macromolecule localization | ribonucleotide metabolic process | response to inorganic substance | establishment of localization in cell | negative regulation of cellular metabolic process | cytoskeleton-dependent intracellular transport | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | negative regulation of phosphatase activity | cellular aromatic compound metabolic process | cellular component organization | cellular response to metal ion | retrograde axonal protein transport | response to stimulus | purine nucleotide metabolic process | retrograde axonal transport | intracellular protein transport | receptor clustering | microtubule-based movement | cellular response to inorganic substance | cellular localization | cellular nitrogen compound metabolic process | negative regulation of metabolic process | purine nucleoside metabolic process | cell-cell signaling | GDP metabolic process | system development | nitrogen compound metabolic process | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | phosphorus metabolic process | regulation of catalytic activity | localization within membrane | protein localization to membrane | organic substance transport | nervous system process | synaptic signaling | organophosphate metabolic process | nucleoside metabolic process | protein transport along microtubule | small molecule metabolic process | peptide transport | nucleobase-containing small molecule metabolic process | sensory perception of pain | establishment or maintenance of cell polarity | phosphate-containing compound metabolic process | receptor localization to synapse | protein localization to synapse | cell communication | regulation of cellular metabolic process | anterograde axonal transport | protein-containing complex localization | neuron maturation | neuron differentiation | nucleoside diphosphate metabolic process | anatomical structure development | metabolic process | developmental maturation | establishment or maintenance of epithelial cell apical/basal polarity | transport along microtubule | cellular protein localization | amide transport | cell adhesion | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of phosphate metabolic process | establishment of protein localization | cell-cell adhesion | sensory perception | axo-dendritic transport | negative regulation of molecular function | signaling | cell development | protein localization | cellular macromolecule localization | developmental process | carbohydrate derivative metabolic process | negative regulation of dephosphorylation | heterocycle metabolic process | negative regulation of hydrolase activity | cellular metabolic process | axonal transport | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | dendrite | synapse | neuron projection | potassium channel complex | somatodendritic compartment | neuromuscular junction | postsynaptic specialization membrane | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | cytoplasm | receptor complex | dendritic tree | main axon | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane bounded cell projection cytoplasm | plasma membrane | postsynaptic density membrane | postsynaptic density | asymmetric synapse | voltage-gated potassium channel complex | cytoplasmic region | integral component of plasma membrane | juxtaparanode region of axon | organelle | axon cytoplasm | postsynaptic specialization | cell periphery | axon | basolateral plasma membrane | ionotropic glutamate receptor complex | transmembrane transporter complex | cation channel complex | ion channel complex | intracellular | cell junction | membrane | intrinsic component of plasma membrane