QuickView for Dnf2 (gene)
- Gene Symbol:
- DNF2
Saccharomyces cerevisiae - Full name:
- Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase
- Synonyms:
- DNF2, YDR093W
- Genomic Location:
- Chr IV: 631279-636117
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cation binding | magnesium ion binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | phospholipid transporter activity | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | transporter activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | metal ion binding | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | phospholipid-translocating ATPase activity
GO Biological Process
lipid transport | establishment of localization | membrane organization | intracellular transport | cellular process | localization | protein transport | response to pheromone | cellular response to pheromone | anion transport | macromolecule localization | regulation of membrane lipid distribution | establishment of localization in cell | regulation of cellular process | cellular component organization | response to stimulus | intracellular protein transport | cellular localization | response to pheromone triggering conjugation with cellular fusion | phospholipid transporter activity | organic substance transport | peptide transport | vesicle-mediated transport | organic anion transport | establishment or maintenance of cell polarity | positive regulation of conjugation with cellular fusion | phospholipid transport | response to organic substance | import into cell | lipid localization | cellular protein localization | amide transport | endocytosis | establishment of protein localization | protein localization | cellular macromolecule localization | phospholipid translocation | lipid transporter activity | ion transport | cellular response to organic substance | phospholipid-translocating ATPase activity
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cellular bud neck | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | cell projection | mating projection | endomembrane system | cellular bud | plasma membrane | site of polarized growth | Golgi membrane | membrane-bounded organelle | organelle | mating projection tip | plasma membrane of cell tip | cell periphery | cell tip | intracellular | mating projection tip membrane | membrane
