QuickView for Dph7 (gene)
- Gene Symbol:
- DPH7
Homo sapiens - Full name:
- diphthamide biosynthesis 7
- Synonyms:
- C9orf112, RRT2, WDR85, diphthine methyltransferase, WD repeat-containing protein 85
- Genomic Location:
- Chr 9: 139569182-139593208
- Description:
-
Diphthamide is a post-translationally modified histidine residue present in elongation factor 2, and is the target of diphtheria toxin. This gene encodes a protein that contains a WD-40 domain, and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase, converting methylated diphthine to diph...
- Orthologs:
- Mus musculus , D. melanogaster , Saccharomyces cerevisiae , Macaca mulatta , Gallus gallus , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
9q34.3
GO Molecular Function
carboxylic ester hydrolase activity | hydrolase activity | catalytic activity | diphthine methylesterase activity | hydrolase activity, acting on ester bonds
GO Biological Process
peptidyl-amino acid modification | cellular process | regulation of cellular process | regulation of metabolic process | regulation of translational elongation | posttranscriptional regulation of gene expression | protein modification process | cellular biosynthetic process | macromolecule modification | nitrogen compound metabolic process | regulation of gene expression | regulation of nitrogen compound metabolic process | biosynthetic process | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | protein metabolic process | metabolic process | organic substance metabolic process | regulation of cytoplasmic translation | cellular protein metabolic process | peptidyl-diphthamide biosynthetic process from peptidyl-histidine | cellular protein modification process | cellular metabolic process | regulation of translation | macromolecule metabolic process
GO Cellular Component
