QuickView for EARS2 (gene)

Gene Symbol:

EARS2 Homo sapiens

Full name:

glutamyl-tRNA synthetase 2, mitochondrial

Synonyms:

COXPD12, MSE1, gluRS, probable glutamate--tRNA ligase, mitochondrial, glutamate tRNA ligase 2, mitochondrial, glutamate--tRNA ligase, probable glutamyl-tRNA synthetase, mitochondrial

Genomic Location:

Chr 16: 23440835-23476197

Description:

This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA...

View Full Description

This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

16p12.2

search → result