QuickView for EEF1A2;jsessionid=465FFD5B164A3A29E5CB79D5E802CE66 (gene)
- Gene Symbol:
- EEF1A2
Homo sapiens - Full name:
- eukaryotic translation elongation factor 1 alpha 2
- Synonyms:
- EEF1AL, EF-1-alpha-2, EF1A, EIEE33, HS1, MRD38, STN, STNL, elongation factor 1-alpha 2, eukaryotic elongation factor 1 A-2, statin-S1
- Genomic Location:
- Chr 20: 61589810-61600949
- Description:
-
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This ge...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Danio rerio , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
20q13.33
GO Molecular Function
kinase binding | guanyl ribonucleotide binding | ribonucleoside binding | translation elongation factor activity | protein kinase binding | enzyme binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | translation factor activity, RNA binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding | RNA binding
GO Biological Process
positive regulation of apoptotic process | regulation of programmed cell death | regulation of autophagy | translational elongation | positive regulation of phosphate metabolic process | translation elongation factor activity | cellular process | positive regulation of catalytic activity | response to inorganic substance | regulation of cellular process | regulation of apoptotic process | regulation of chaperone-mediated autophagy | regulation of metabolic process | response to stimulus | peptide biosynthetic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | regulation of catalytic activity | regulation of phosphorylation | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | cellular amide metabolic process | translation | translation factor activity, RNA binding | biosynthetic process | regulation of lipid kinase activity | regulation of cellular metabolic process | regulation of protein metabolic process | peptide metabolic process | positive regulation of molecular function | protein metabolic process | regulation of kinase activity | metabolic process | regulation of protein catabolic process | positive regulation of cell death | organic substance metabolic process | gene expression | amide biosynthetic process | positive regulation of programmed cell death | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of phosphorylation | cellular protein metabolic process | cellular macromolecule biosynthetic process | positive regulation of lipid kinase activity | response to electrical stimulus | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | cellular metabolic process | regulation of cell death | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | somatodendritic compartment | organelle membrane | cell body | cell | cytoplasmic side of membrane | neuronal cell body | cytoplasm | intracellular organelle | eukaryotic translation elongation factor 1 complex | protein-containing complex | vacuole | lytic vacuole | membrane-bounded organelle | cytoplasmic side of lysosomal membrane | nucleus | organelle | lysosome | intracellular | myelin sheath | lysosomal membrane | membrane | vacuolar membrane
