QuickView for EF-Ts (gene)
- Gene Symbol:
- TSFM
Homo sapiens - Full name:
- Ts translation elongation factor, mitochondrial
- Synonyms:
- EFTS, EFTSMT, elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt, mitochondrial elongation factor Ts
- Genomic Location:
- Chr 12: 56462826-56476784
- Description:
-
This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndro...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
12q14.1
GO Molecular Function
translation elongation factor activity | nucleic acid binding | translation factor activity, RNA binding | organic cyclic compound binding | protein binding | heterocyclic compound binding | RNA binding
GO Biological Process
regulation of mitochondrial translation | translational elongation | translation elongation factor activity | cellular process | regulation of cellular process | regulation of metabolic process | mitochondrial translational elongation | peptide biosynthetic process | mitochondrial translation | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | cellular nitrogen compound metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | regulation of nitrogen compound metabolic process | cellular amide metabolic process | translation | translation factor activity, RNA binding | biosynthetic process | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | peptide metabolic process | regulation of RNA metabolic process | protein metabolic process | metabolic process | mitochondrial gene expression | regulation of RNA biosynthetic process | organic substance metabolic process | gene expression | amide biosynthetic process | regulation of DNA-templated transcription, elongation | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | cellular metabolic process | regulation of translation | macromolecule metabolic process
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
