QuickView for EFNA3;jsessionid=E5FAD69DFBA8D4AC818F15CB79155DA4 (gene)

Gene Symbol:

EFNA3 Homo sapiens

Full name:

ephrin A3

Synonyms:

EFL2, EPLG3, Ehk1-L, LERK3, ephrin-A3, EFL-2, EHK1 ligand, LERK-3, eph-related receptor tyrosine kinase ligand 3, ligand of eph-related kinase 3

Genomic Location:

Chr 1: 153317972-153326638

Description:

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided...

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This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACGCACA_MIR210 ,  CTATGCA_MIR153 ,  GTGACTT_MIR224 ,  AACTGGA_MIR145 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  ATGTACA_MIR493 ,  TTGGAGA_MIR5155P_MIR519E ,  CACCCBINDINGFACTOR_Q6 ,  GGGYGTGNY_UNKNOWN ,  LFA1_Q6 ,  GGGCGGR_SP1_Q6 ,  RORA1_01 ,  CP2_02 ,  TGCTTTG_MIR330 ,  E2F_Q2 ,  ER_Q6_02 ,  SP1_Q6_01 ,  NFKB_C ,  ETF_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-210 ,  Predicted Gene Targets for miR-224 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-330 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-493-5p

miRNA binding sites
(Source: miRecords):

hsa-miR-210 Targeted Genes

Cytogenetic Map:

1q21.3

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