QuickView for EGR3;jsessionid=546F649770729EDEECC87F580F6DE192 (gene)

Gene Symbol:

EGR3 Homo sapiens

Full name:

early growth response 3

Synonyms:

EGR-3, PILOT, early growth response protein 3, zinc finger protein pilot

Genomic Location:

Chr 8: 22601119-22606760

Description:

This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in ...

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This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CGTSACG_PAX3_B ,  AACWWCAANK_UNKNOWN ,  PBX1_02 ,  CMYB_01 ,  TTTGCAG_MIR518A2 ,  SRF_01 ,  ATF6_01 ,  RYTTCCTG_ETS2_B ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  E2F1_Q4_01 ,  SYATTGTG_UNKNOWN ,  SRF_Q6 ,  TTCNRGNNNNTTC_HSF_Q6 ,  AGCGCTT_MIR518F_MIR518E_MIR518A ,  NGFIC_01 ,  YGACNNYACAR_UNKNOWN ,  CTTTGCA_MIR527 ,  TTTGTAG_MIR520D ,  YATTNATC_UNKNOWN ,  TGAGATT_MIR216 ,  ACTTTAT_MIR1425P ,  RYCACNNRNNRNCAG_UNKNOWN ,  MYCMAX_B ,  EGR2_01 ,  CREB_Q4 ,  WHN_B ,  HNF4_DR1_Q3 ,  GGGAGGRR_MAZ_Q6 ,  CREBP1_Q2 ,  CDPCR3HD_01 ,  RGAANNTTC_HSF1_01 ,  STAT3_02 ,  TAATGTG_MIR323 ,  CATTTCA_MIR203 ,  CAGGTA_AREB6_01 ,  GTGACGY_E4F1_Q6 ,  RREB1_01 ,  ATF_01 ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  HSF1_01 ,  YY1_01 ,  AP2_Q6_01 ,  GTCTTCC_MIR7 ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  GACAATC_MIR219 ,  SRF_Q4 ,  ATGTTTC_MIR494 ,  NERF_Q2 ,  E4F1_Q6 ,  E2F1_Q3_01 ,  HSF2_01 ,  AHRARNT_01 ,  RNGTGGGC_UNKNOWN ,  AATGTGA_MIR23A_MIR23B ,  TTGCCAA_MIR182 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GATA4_Q3 ,  CCAGGGG_MIR331 ,  CREB_Q2 ,  IK3_01 ,  AGCGCAG_MIR191 ,  CTGCAGY_UNKNOWN ,  PAX_Q6 ,  GTGGGTGK_UNKNOWN ,  SRF_Q5_01 ,  TCCATTKW_UNKNOWN ,  WCAANNNYCAG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  EGR1_01 ,  P300_01 ,  AACTTT_UNKNOWN ,  MZF1_02 ,  E2F_Q3_01 ,  RRCCGTTA_UNKNOWN ,  NFKB_C ,  EGR3_01 ,  SRF_C ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-146 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-216 ,  Predicted Gene Targets for miR-219 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-331 ,  Predicted Gene Targets for miR-335 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-380-5p

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Cytogenetic Map:

8p21.3

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