QuickView for EHHADH (gene)

Gene Symbol:

EHHADH Homo sapiens

Full name:

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

Synonyms:

ECHD, FRTS3, L-PBE, LBFP, LBP, PBFE, peroxisomal bifunctional enzyme, 3,2-trans-enoyl-CoA isomerase, L-3-hydroxyacyl-CoA dehydrogenase, L-bifunctional protein, peroxisomal, PBE, enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase, enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase, peroxisomal enoyl-CoA hydratase

Genomic Location:

Chr 3: 186391106-186454531

Description:

The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorder...

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The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

3q27.2

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