QuickView for ELP3 (gene)
- Gene Symbol:
- ELP3
Homo sapiens - Full name:
- elongator acetyltransferase complex subunit 3
- Synonyms:
- KAT9, elongator complex protein 3, elongation protein 3 homolog
- Genomic Location:
- Chr 8: 28006645-28104585
- Description:
-
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
8p21.1
GO Molecular Function
RNA polymerase II complex binding | phosphorylase kinase regulator activity | protein kinase regulator activity | cofactor binding | N-acetyltransferase activity | RNA polymerase binding | cation binding | transferase activity, transferring acyl groups other than amino-acyl groups | kinase regulator activity | N-acyltransferase activity | enzyme binding | molecular function regulator | catalytic activity | transferase activity, transferring acyl groups | histone acetyltransferase activity | iron-sulfur cluster binding | RNA polymerase core enzyme binding | ion binding | peptide N-acetyltransferase activity | protein binding | transferase activity | peptide-lysine-N-acetyltransferase activity | enzyme regulator activity | metal ion binding | basal RNA polymerase II transcription machinery binding | acetyltransferase activity
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of locomotion | RNA processing | cell motility | phosphorylase kinase regulator activity | regulation of localization | protein kinase regulator activity | peptidyl-amino acid modification | tRNA modification | neuron migration | histone modification | cell differentiation | nervous system development | neurogenesis | positive regulation of cellular component movement | generation of neurons | cellular process | regulation of cell motility | localization | chromatin organization | kinase regulator activity | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | RNA modification | cellular nitrogen compound biosynthetic process | ncRNA processing | peptidyl-lysine acetylation | cellular nitrogen compound metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | molecular function regulator | regulation of nucleic acid-templated transcription | locomotion | system development | nitrogen compound metabolic process | multicellular organism development | protein acetylation | cell migration | regulation of catalytic activity | regulation of phosphorylation | histone acetyltransferase activity | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of cell migration | histone acetylation | internal peptidyl-lysine acetylation | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation | transcription elongation from RNA polymerase II promoter | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | tRNA processing | regulation of locomotion | regulation of RNA metabolic process | tRNA metabolic process | protein metabolic process | regulation of kinase activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | regulation of phosphate metabolic process | transcription, DNA-templated | covalent chromatin modification | regulation of transcription, DNA-templated | internal protein amino acid acetylation | cellular protein metabolic process | enzyme regulator activity | cellular macromolecule biosynthetic process | tRNA wobble uridine modification | developmental process | organelle organization | cellular protein modification process | ncRNA metabolic process | heterocycle metabolic process | central nervous system development | chromosome organization | cellular metabolic process | positive regulation of cell motility | macromolecule metabolic process | multicellular organismal process | DNA-templated transcription, elongation | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | transcription elongation factor complex | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | Elongator holoenzyme complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
