QuickView for EPHA1 (gene)

Gene Symbol:

EPHA1 Homo sapiens

Full name:

EPH receptor A1

Synonyms:

EPH, EPHT, EPHT1, ephrin type-A receptor 1, eph tyrosine kinase 1, erythropoietin-producing hepatoma amplified sequence, erythropoietin-producing hepatoma receptor, hEpha1, oncogene EPH, soluble EPHA1 variant 1, soluble EPHA1 variant 2, tyrosine-protein kinase receptor EPH

Genomic Location:

Chr 7: 142798327-142816107

Description:

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibron...

View Full Description

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_C ,  TFIIA_Q6 ,  TGANTCA_AP1_C ,  STAT1_02 ,  STAT1_03 ,  GGGAGGRR_MAZ_Q6 ,  CAGGTG_E12_Q6 ,  SP1_Q4_01 ,  CTTTAAR_UNKNOWN ,  AP2REP_01 ,  PAX5_01 ,  CTGYNNCTYTAA_UNKNOWN ,  GTGGGTGK_UNKNOWN ,  FOXM1_01 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  GGGTGGRR_PAX4_03

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15

Cytogenetic Map:

7q34-q35

search → result