QuickView for ERAP2;jsessionid=E9152983EFAE77349246CE7A860EE193 (gene)

Gene Symbol:

ERAP2 Homo sapiens

Full name:

endoplasmic reticulum aminopeptidase 2

Synonyms:

L-RAP, LRAP, endoplasmic reticulum aminopeptidase 2, leukocyte-derived arginine aminopeptidase

Genomic Location:

Chr 5: 96241024-96279397

Description:

This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spo...

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This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5.

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Orthologs:

Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

5q15

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