QuickView for Edc3 (gene)

Gene Symbol:

EDC3 Homo sapiens

Full name:

enhancer of mRNA decapping 3

Synonyms:

LSM16, MRT50, YJDC, YJEFN2, hYjeF_N2-15q23, enhancer of mRNA-decapping protein 3, LSM16 homolog (EDC3, S. cerevisiae), enhancer of mRNA decapping 3 homolog, yjeF N-terminal domain-containing protein 2, yjeF domain containing, yjeF domain-containing protein 1

Genomic Location:

Chr 15: 72709952-72775413

Description:

This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of in...

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This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  MGGAAGTG_GABP_B ,  GGCAGCT_MIR22 ,  NRF2_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C

Cytogenetic Map:

15q24.1

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