QuickView for Elk3 (gene)

Gene Symbol:

ELK3 Homo sapiens

Full name:

ELK3, ETS transcription factor

Synonyms:

ERP, NET, SAP-2, SAP2, ETS domain-containing protein Elk-3, ELK3, ETS-domain protein (SRF accessory protein 2), ETS-related protein ERP, ETS-related protein NET, SRF accessory protein 2, serum response factor accessory protein 2

Genomic Location:

Chr 12: 95112338-95185740

Description:

This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a tr...

View Full Description

This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  GABP_B ,  RTAAACA_FREAC2_01 ,  OCT1_05 ,  FREAC7_01 ,  TTTGCAC_MIR19A_MIR19B ,  TGANTCA_AP1_C ,  AAGCCAT_MIR135A_MIR135B ,  ETS_Q4 ,  TTANTCA_UNKNOWN ,  RYTTCCTG_ETS2_B ,  P53_DECAMER_Q2 ,  NFAT_Q6 ,  HOXA4_Q2 ,  AP1_Q6 ,  TAAYNRNNTCC_UNKNOWN ,  TTGCACT_MIR130A_MIR301_MIR130B ,  CTTTGA_LEF1_Q2 ,  GCCATNTTG_YY1_Q6 ,  TCF4_Q5 ,  GGGAGGRR_MAZ_Q6 ,  RGAANNTTC_HSF1_01 ,  AP1_Q6_01 ,  LEF1_Q6 ,  PAX4_02 ,  P53_02 ,  CDX2_Q5 ,  CAGGTG_E12_Q6 ,  WYAAANNRNNNGCG_UNKNOWN ,  ZID_01 ,  TGCCTTA_MIR124A ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  AP1_Q2_01 ,  OCT1_03 ,  CCCNNGGGAR_OLF1_01 ,  NERF_Q2 ,  E2F1_Q3_01 ,  MGGAAGTG_GABP_B ,  ACTGAAA_MIR30A3P_MIR30E3P ,  AP1_Q4 ,  AHRARNT_01 ,  GTGCCTT_MIR506 ,  BACH1_01 ,  MTF1_Q4 ,  ELK1_01 ,  MYOGENIN_Q6 ,  SCGGAAGY_ELK1_02 ,  CTGCAGY_UNKNOWN ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  AP1_Q2 ,  TGACAGNY_MEIS1_01 ,  RNTCANNRNNYNATTW_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  ER_Q6_02 ,  SMAD_Q6 ,  AACTTT_UNKNOWN ,  PAX4_03 ,  ETS1_B ,  PAX2_02 ,  AP1_Q4_01 ,  GGGTGGRR_PAX4_03 ,  OLF1_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u

Cytogenetic Map:

12q23.1

search → result