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QuickView for FCGR1A (gene)


Gene Symbol:
FCGR1A Homo sapiens Homo sapiens
Full name:
Fc fragment of IgG receptor Ia
Synonyms:
CD64, CD64A, FCRI, IGFR1, high affinity immunoglobulin gamma Fc receptor I, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64), Fc gamma receptor Ia, Fc-gamma RI, Fc-gamma receptor I A1, IgG Fc receptor I, fc-gamma RIA, fcgammaRIa
Genomic Location:
Chr 1: 148020912-148030698
Description:
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Orthologs:
Mus musculus Rattus norvegicus Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q21.2





GO Molecular Function

protein-containing complex binding | immunoglobulin binding | protein binding | IgG binding

GO Biological Process

positive regulation of immune response | response to cytokine | antigen processing and presentation | immune response-regulating signaling pathway | phagocytosis, engulfment | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | immune response-activating cell surface receptor signaling pathway | defense response | membrane organization | cellular process | Fc-gamma receptor signaling pathway involved in phagocytosis | localization | regulation of immune response | regulation of cellular process | interferon-gamma-mediated signaling pathway | cellular component organization | cellular response to interferon-gamma | response to stimulus | positive regulation of immune system process | response to stress | immune response-activating signal transduction | Fc-gamma receptor signaling pathway | antigen processing and presentation of exogenous peptide antigen via MHC class I | cytokine-mediated signaling pathway | vesicle-mediated transport | cellular response to cytokine stimulus | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | cell communication | antigen processing and presentation of exogenous antigen | activation of immune response | response to organic substance | import into cell | antigen processing and presentation of peptide antigen via MHC class I | cell surface receptor signaling pathway | membrane invagination | endocytosis | immune response | response to interferon-gamma | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | signaling | receptor-mediated endocytosis | Fc receptor signaling pathway | Fc receptor mediated stimulatory signaling pathway | innate immune response | antigen processing and presentation of peptide antigen | immune system process | cellular response to organic substance | phagocytosis | signal transduction

GO Cellular Component

integral component of membrane | early endosome membrane | clathrin-coated endocytic vesicle membrane | endocytic vesicle membrane | clathrin-coated vesicle membrane | organelle membrane | clathrin-coated vesicle | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | clathrin-coated endocytic vesicle | intracellular organelle | endosome membrane | endomembrane system | plasma membrane | vesicle | endosome | coated vesicle membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | early endosome | intracellular vesicle | endocytic vesicle | intracellular | membrane | cytoplasmic vesicle membrane | coated vesicle