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QuickView for FCGR2A (gene)


Gene Symbol:
FCGR2A Homo sapiens Homo sapiens
Full name:
Fc fragment of IgG receptor IIa
Synonyms:
CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2, low affinity immunoglobulin gamma Fc region receptor II-a, Fc fragment of IgG, low affinity IIa, receptor (CD32), Immunoglobulin G Fc receptor II, fc-gamma-RIIa, fcRII-a, igG Fc receptor II-a
Genomic Location:
Chr 1: 159741844-159755984
Description:
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splic...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1q23.3





GO Molecular Function

protein-containing complex binding | immunoglobulin binding | protein binding | IgG binding

GO Biological Process

positive regulation of immune response | exocytosis | immune response-regulating signaling pathway | neutrophil activation | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | immune response-activating cell surface receptor signaling pathway | cellular process | secretion | Fc-gamma receptor signaling pathway involved in phagocytosis | leukocyte degranulation | localization | regulation of immune response | regulation of cellular process | leukocyte activation | response to stimulus | neutrophil degranulation | positive regulation of immune system process | leukocyte activation involved in immune response | secretion by cell | immune response-activating signal transduction | leukocyte mediated immunity | Fc-gamma receptor signaling pathway | vesicle-mediated transport | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | regulated exocytosis | cell communication | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | activation of immune response | import into cell | cell surface receptor signaling pathway | endocytosis | immune response | cell activation | signaling | Fc receptor signaling pathway | Fc receptor mediated stimulatory signaling pathway | neutrophil mediated immunity | immune system process | phagocytosis | signal transduction

GO Cellular Component

secretory granule | integral component of membrane | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | secretory granule membrane | secretory vesicle | endomembrane system | plasma membrane | vesicle | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane