QuickView for FGF9;jsessionid=BFEEE34581159281BC59D69BB6351338 (gene)

Gene Symbol:

FGF9 Homo sapiens

Full name:

fibroblast growth factor 9

Synonyms:

FGF-9, GAF, HBFG-9, HBGF-9, SYNS3, fibroblast growth factor 9, fibroblast growth factor 9 (glia-activating factor), heparin-binding growth factor 9

Genomic Location:

Chr 13: 21143875-21174187

Description:

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as...

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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

FOXO1_02 ,  RTAAACA_FREAC2_01 ,  FREAC7_01 ,  HNF3ALPHA_Q6 ,  AP1_C ,  TGANTCA_AP1_C ,  MYOD_01 ,  TAL1ALPHAE47_01 ,  GNCF_01 ,  P53_DECAMER_Q2 ,  EFC_Q6 ,  VDR_Q3 ,  TGANNYRGCA_TCF11MAFG_01 ,  FOXO4_01 ,  CATTGTYY_SOX9_B1 ,  FOXD3_01 ,  HFH1_01 ,  VDR_Q6 ,  AREB6_04 ,  AMEF2_Q6 ,  CREB_Q4 ,  TGACCTY_ERR1_Q2 ,  E2F1_Q4 ,  GGGAGGRR_MAZ_Q6 ,  RGAANNTTC_HSF1_01 ,  NFE2_01 ,  CEBPB_01 ,  AP1_Q6_01 ,  TAL1BETAE47_01 ,  CDP_02 ,  ATGCTGG_MIR338 ,  FOXO3_01 ,  CAGGTA_AREB6_01 ,  RP58_01 ,  FREAC3_01 ,  ATF_01 ,  RFX1_02 ,  CAGGTG_E12_Q6 ,  AP1_01 ,  DR1_Q3 ,  GR_Q6 ,  TGCGCANK_UNKNOWN ,  AP2_Q6_01 ,  HNF3_Q6 ,  FOXJ2_01 ,  TGCTGAY_UNKNOWN ,  E4F1_Q6 ,  AHR_Q5 ,  FOXO1_01 ,  IRF_Q6 ,  CTTTAAR_UNKNOWN ,  E47_01 ,  GCCNNNWTAAR_UNKNOWN ,  POU1F1_Q6 ,  SOX5_01 ,  NRF2_Q4 ,  RORA1_01 ,  AREB6_03 ,  TTGCCAA_MIR182 ,  FREAC2_01 ,  TTGTTT_FOXO4_01 ,  PIT1_Q6 ,  ARGGGTTAA_UNKNOWN ,  TEF_Q6 ,  CREB_Q2 ,  CP2_02 ,  CTGCAGY_UNKNOWN ,  TAL1BETAITF2_01 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  ICSBP_Q6 ,  CTTTGT_LEF1_Q2 ,  ER_Q6_01 ,  ISRE_01 ,  MMEF2_Q6 ,  SRY_02 ,  AACTTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  PPAR_DR1_Q2 ,  ERR1_Q2 ,  ER_Q6 ,  TCF1P_Q6 ,  PAX2_02 ,  TGACCTTG_SF1_Q6 ,  GTTNYYNNGGTNA_UNKNOWN ,  FREAC4_01 ,  FOXO4_02 ,  SF1_Q6 ,  TCF11MAFG_01 ,  TGASTMAGC_NFE2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-338 ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182

Cytogenetic Map:

13q12.11

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