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QuickView for FKBP38 (gene)


Gene Symbol:
FKBP8 Homo sapiens Homo sapiens
Full name:
FK506 binding protein 8
Synonyms:
FKBP38, FKBPr38, peptidyl-prolyl cis-trans isomerase FKBP8, 38 kDa FK506-binding protein, 38 kDa FKBP, FK506 binding protein 8, 38kDa, FKBP-38, FKBP-8, PPIase FKBP8, hFKBP38, rotamase
Genomic Location:
Chr 19: 18503568-18515383
Description:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memo...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19p13.11





GO Molecular Function

cation binding | disordered domain specific binding | protein domain specific binding | identical protein binding | ion binding | protein binding | metal ion binding

GO Biological Process

negative regulation of phosphorylation | intracellular signal transduction | regulation of programmed cell death | peptidyl-amino acid modification | eye development | negative regulation of cellular process | neural tube patterning | cell differentiation | nervous system development | multicellular organism growth | negative regulation of protein phosphorylation | pattern specification process | cellular process | cell fate specification | developmental growth | peptidyl-proline modification | negative regulation of apoptotic process | negative regulation of cellular metabolic process | tissue development | interspecies interaction between organisms | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | epithelium development | response to stimulus | programmed cell death | negative regulation of metabolic process | positive regulation of BMP signaling pathway | protein modification process | dorsal/ventral pattern formation | embryo development | macromolecule modification | regulation of nucleic acid-templated transcription | apoptotic process | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | multicellular organism development | regulation of BMP signaling pathway | regulation of phosphorylation | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | neural tube development | regulation of cellular protein metabolic process | sensory organ development | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | dorsal/ventral neural tube patterning | positive regulation of signal transduction | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | viral process | regulation of cellular response to growth factor stimulus | protein metabolic process | regionalization | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of programmed cell death | organic substance metabolic process | cell death | animal organ development | negative regulation of cellular protein metabolic process | regulation of phosphate metabolic process | camera-type eye development | smoothened signaling pathway | negative regulation of protein metabolic process | regulation of cell communication | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | developmental process | cellular protein modification process | tube development | protein peptidyl-prolyl isomerization | cellular metabolic process | regulation of cell death | negative regulation of cell death | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | integral component of endoplasmic reticulum membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | intrinsic component of endoplasmic reticulum membrane | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | cytosol | intracellular | membrane