QuickView for FLK1 (gene)
- Gene Symbol:
- TUP1
Saccharomyces cerevisiae - Full name:
- General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes
- Synonyms:
- AAR1, AER2, AMM1, CRT4, CYC9, FLK1, ROX4, SFL2, TUP1, TUP1, UMR7, YCR084C
- Genomic Location:
- Chr III: 260308-262449
- Orthologs:
- Schizosaccharomyces pombe
- External Links:
- Entrez Gene
GO Molecular Function
transcription factor activity, transcription factor binding | transcription factor activity, RNA polymerase II transcription factor binding | mediator complex binding | enzyme binding | protein-containing complex binding | lipid binding | transcriptional repressor activity, RNA polymerase II transcription factor binding | phospholipid binding | anion binding | phosphatidylinositol bisphosphate binding | ion binding | protein binding | phosphatidylinositol binding | histone binding | phosphatidylinositol-3,5-bisphosphate binding | histone deacetylase binding | phosphatidylinositol phosphate binding
GO Biological Process
RNA metabolic process | response to extracellular stimulus | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | response to nutrient levels | developmental process involved in reproduction | regulation of localization | nucleosome organization | regulation of mating-type specific transcription, DNA-templated | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cell differentiation | cellular response to extracellular stimulus | negative regulation of mating-type specific transcription from RNA polymerase II promoter | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | carbon catabolite repression of transcription by glucose | negative regulation of nucleic acid-templated transcription | negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | regulation of transcription from RNA polymerase II promoter by glucose | cellular component organization | carbon catabolite repression of transcription from RNA polymerase II promoter by glucose | response to stimulus | regulation of fatty acid biosynthetic process | regulation of invasive growth in response to glucose limitation | transcriptional repressor activity, RNA polymerase II transcription factor binding | cellular nitrogen compound biosynthetic process | mating type determination | reproduction | cellular nitrogen compound metabolic process | negative regulation of transport | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | regulation of peptide transport | cellular biosynthetic process | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | cellular response to nutrient levels | nitrogen compound metabolic process | reproductive process | carbon catabolite regulation of transcription from RNA polymerase II promoter | ATP-dependent chromatin remodeling | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | response to nutrient | regulation of fatty acid metabolic process | carbon catabolite regulation of transcription | biosynthetic process | aromatic compound biosynthetic process | negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter | sex determination | cell communication | regulation of cellular metabolic process | chromatin remodeling | nucleosome positioning | regulation of RNA metabolic process | regulation of lipid biosynthetic process | cellular response to nutrient | regulation of growth | chromatin assembly or disassembly | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | DNA packaging | transcription, DNA-templated | chromatin assembly | regulation of dipeptide transport | negative regulation of transcription from RNA polymerase II promoter by glucose | regulation of transcription, DNA-templated | histone exchange | cellular macromolecule biosynthetic process | regulation of cellular ketone metabolic process | developmental process | organelle organization | negative regulation of transcription by RNA polymerase II | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | DNA conformation change | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of transcription by glucose | carbon catabolite repression of transcription | regulation of lipid metabolic process | positive regulation of metabolic process | chromosome organization | regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter | regulation of filamentous growth | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | protein-containing complex | membrane-bounded organelle | transcriptional repressor complex | nucleus | organelle | intracellular
