QuickView for FRS2;jsessionid=691AC382CF94BD7CA87A5E7166E0D10F (gene)
- Gene Symbol:
- FRS2
Homo sapiens - Full name:
- fibroblast growth factor receptor substrate 2
- Synonyms:
- FRS1A, FRS2A, FRS2alpha, SNT, SNT-1, SNT1, fibroblast growth factor receptor substrate 2, FGFR signalling adaptor, FGFR substrate 2, FGFR-signaling adaptor SNT, suc1-associated neurotrophic factor target 1
- Genomic Location:
- Chr 12: 68150396-68259829
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
12q15
GO Molecular Function
guanyl-nucleotide exchange factor activity | kinase binding | enzyme activator activity | GTPase binding | protein kinase binding | receptor tyrosine kinase binding | enzyme binding | transmembrane receptor protein tyrosine kinase adaptor activity | signaling receptor binding | phosphatase activator activity | cytokine receptor binding | Ras GTPase binding | molecular function regulator | catalytic activity | signaling adaptor activity | protein binding, bridging | neurotrophin receptor binding | neurotrophin TRKA receptor binding | phosphatidylinositol 3-kinase activity | fibroblast growth factor receptor binding | protein tyrosine kinase binding | molecular adaptor activity | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | protein binding | 1-phosphatidylinositol-3-kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | Ras guanyl-nucleotide exchange factor activity | transferase activity | small GTPase binding | enzyme regulator activity | growth factor receptor binding | kinase activity | phosphatase regulator activity
GO Biological Process
regulation of ERK1 and ERK2 cascade | brain development | transmembrane receptor protein tyrosine phosphatase signaling pathway | cell morphogenesis | guanyl-nucleotide exchange factor activity | ectodermal placode formation | neuron projection morphogenesis | developmental process involved in reproduction | intracellular signal transduction | enzyme activator activity | morphogenesis of an epithelium | regulation of programmed cell death | regulation of cardiac muscle cell differentiation | eye development | phosphatidylinositol metabolic process | negative regulation of cellular process | positive regulation of developmental process | embryonic camera-type eye morphogenesis | regulation of MAP kinase activity | cell differentiation | nervous system development | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | phosphatidylinositol-3-phosphate biosynthetic process | phospholipid metabolic process | pattern specification process | cellular process | negative regulation of muscle organ development | cell projection morphogenesis | neuron development | reproductive system development | regulation of striated muscle tissue development | positive regulation of protein kinase activity | axon guidance | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cell differentiation | regulation of protein kinase B signaling | regulation of cellular process | negative regulation of cardiocyte differentiation | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | cellular lipid metabolic process | prostate gland epithelium morphogenesis | MAPK cascade | urogenital system development | head development | negative regulation of cardiac muscle tissue development | response to stimulus | cell morphogenesis involved in neuron differentiation | transmembrane receptor protein tyrosine kinase adaptor activity | cellular response to fibroblast growth factor stimulus | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | negative regulation of striated muscle cell differentiation | gland morphogenesis | phosphatase activator activity | neuron projection guidance | regulation of cell proliferation | epithelial cell development | reproduction | blastoderm segmentation | negative regulation of muscle tissue development | G-protein coupled receptor signaling pathway | positive regulation of protein serine/threonine kinase activity | protein modification process | optic placode formation | cellular biosynthetic process | embryo development | macromolecule modification | activation of protein kinase activity | molecular function regulator | anterior/posterior pattern specification | locomotion | signaling adaptor activity | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | regulation of MAPK cascade | neuroblast proliferation | phosphorus metabolic process | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | fibroblast growth factor receptor signaling pathway | stem cell proliferation | axon development | embryonic axis specification | negative regulation of cardiac muscle cell differentiation | branching involved in prostate gland morphogenesis | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | ectodermal placode development | animal organ morphogenesis | phospholipid biosynthetic process | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | phosphatidylinositol 3-kinase activity | axonogenesis | embryonic camera-type eye development | cell proliferation | biosynthetic process | regulation of cellular protein metabolic process | neurotrophin signaling pathway | phosphorylation | lipid biosynthetic process | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | sensory organ development | gastrulation with mouth forming second | lipid phosphorylation | optic placode formation involved in camera-type eye formation | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | eye morphogenesis | anterior/posterior axis specification | activation of MAPKK activity | regulation of protein metabolic process | positive regulation of signal transduction | negative regulation of striated muscle tissue development | heart development | lipid modification | regulation of protein phosphorylation | glycerolipid metabolic process | embryonic morphogenesis | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | positive regulation of molecular function | neuron differentiation | activation of MAPK activity | embryonic organ morphogenesis | ventricular septum development | protein metabolic process | regionalization | cardiac ventricle development | axis specification | positive regulation of protein modification process | response to organic substance | gland development | regulation of cardiac muscle tissue development | neurotrophin TRK receptor signaling pathway | tissue morphogenesis | glycerophospholipid biosynthetic process | 1-phosphatidylinositol-3-kinase activity | regulation of kinase activity | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | embryonic organ development | lens fiber cell development | Ras guanyl-nucleotide exchange factor activity | neuron projection development | embryonic camera-type eye formation | organic substance metabolic process | animal organ development | forebrain development | anterior/posterior axis specification, embryo | positive regulation of kinase activity | neural precursor cell proliferation | regulation of striated muscle cell differentiation | regulation of phosphate metabolic process | phosphatidylinositol biosynthetic process | prostate gland morphogenesis | positive regulation of MAPK cascade | morphogenesis of a branching epithelium | camera-type eye development | anatomical structure formation involved in morphogenesis | regulation of animal organ formation | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | regulation of cell communication | signaling | cell development | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | phosphatidylinositol phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | camera-type eye morphogenesis | positive regulation of MAP kinase activity | reproductive structure development | regulation of developmental process | glycerophospholipid metabolic process | kinase activity | segmentation | developmental process | regulation of muscle cell differentiation | cardiac septum development | cellular protein modification process | response to fibroblast growth factor | epithelial cell differentiation | cardiac chamber development | central nervous system development | negative regulation of muscle cell differentiation | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | organ induction | gastrulation | cellular metabolic process | embryonic eye morphogenesis | cellular response to organic substance | regulation of cell death | lens fiber cell differentiation | developmental induction | circulatory system development | chemotaxis | negative regulation of cell differentiation | lens development in camera-type eye | phosphatase regulator activity | positive regulation of signaling | signal transduction | regulation of signaling | embryonic pattern specification | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | adherens junction | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | cell-cell adherens junction | cell-cell junction | endomembrane system | plasma membrane | vesicle | integral component of plasma membrane | endosome | membrane-bounded organelle | organelle | cell periphery | cytosol | intracellular vesicle | intracellular | cell junction | membrane | intrinsic component of plasma membrane
