QuickView for FXR1 (gene)

Gene Symbol:

FXR1 Homo sapiens

Full name:

FMR1 autosomal homolog 1

Synonyms:

FXR1P, fragile X mental retardation syndrome-related protein 1, FXR1/MYC fusion, fragile X mental retardation autosomal homolog variant p1K, fragile X mental retardation autosomal homolog variant p2K, fragile X mental retardation autosomal homolog variant p4K, fragile X mental retardation autosomal homolog variant p5FK, fragile X mental retardation, autosomal homolog 1, hFXR1p

Genomic Location:

Chr 3: 182113146-182177644

Description:

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  SMAD3_Q6 ,  CTACTGT_MIR199A ,  TAGCTTT_MIR9 ,  TAAWWATAG_RSRFC4_Q2 ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  MYCMAX_02 ,  ATGTTAA_MIR302C ,  ACTGAAA_MIR30A3P_MIR30E3P ,  GACTGTT_MIR212_MIR132 ,  TTGCCAA_MIR182 ,  TTGTTT_FOXO4_01 ,  PIT1_Q6 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  TGACAGNY_MEIS1_01 ,  CAGCTG_AP4_Q5 ,  MMEF2_Q6 ,  GGCAGTG_MIR3243P ,  RRCCGTTA_UNKNOWN ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

3q26.33

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