QuickView for Flt3 ligand (gene)

Gene Symbol:

FLT3LG Homo sapiens

Full name:

fms related tyrosine kinase 3 ligand

Synonyms:

FL, FLG3L, FLT3L, fms-related tyrosine kinase 3 ligand, flt3 ligand

Genomic Location:

Chr 19: 54669298-54681300

Description:

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counter...

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Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).

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Orthologs:

Mus musculus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Rattus norvegicus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_01 ,  RYTTCCTG_ETS2_B ,  AP2GAMMA_01 ,  AP4_01 ,  TTCYNRGAA_STAT5B_01 ,  TGACAGNY_MEIS1_01 ,  CCANNAGRKGGC_UNKNOWN ,  STTTCRNTTT_IRF_Q6 ,  IRF2_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-381

Cytogenetic Map:

19q13.33

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