QuickView for Fucose-1-phosphate guanylyltransferase (gene)
- Gene Symbol:
- FPGT
Homo sapiens - Full name:
- fucose-1-phosphate guanylyltransferase
- Synonyms:
- GFPP, fucose-1-phosphate guanylyltransferase, GDP-L-fucose diphosphorylase, GDP-beta-L-fucose pyrophosphorylase, fucose-1-phosphate guanyltransferase
- Genomic Location:
- Chr 1: 74436514-74445708
- Description:
-
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pat...
- Orthologs:
- Mus musculus , Rattus norvegicus , C. elegans , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1p31.1
GO Molecular Function
guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | nucleotidyltransferase activity | catalytic activity | anion binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | fucose-1-phosphate guanylyltransferase activity | transferase activity, transferring phosphorus-containing groups | GTP binding | transferase activity | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding
GO Biological Process
fucose metabolic process | monosaccharide metabolic process | small molecule metabolic process | carbohydrate metabolic process | metabolic process | hexose metabolic process | organic substance metabolic process
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
