QuickView for GAB1 (gene)

Gene Symbol:

GAB1 Homo sapiens

Full name:

GRB2 associated binding protein 1

Synonyms:

GRB2-associated-binding protein 1, GRB2-associated binder 1, growth factor receptor bound protein 2-associated protein 1

Genomic Location:

Chr 4: 144477500-144610729

Description:

The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATGTACA_MIR493 ,  GCACCTT_MIR18A_MIR18B ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  TGGTGCT_MIR29A_MIR29B_MIR29C

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-18 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

4q31.21

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