QuickView for GABABR2 (gene)
- Gene Symbol:
- GABBR2
Homo sapiens - Full name:
- gamma-aminobutyric acid type B receptor subunit 2
- Synonyms:
- GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, gamma-aminobutyric acid type B receptor subunit 2, G-protein coupled receptor 51, GABA-B receptor 2, GABA-B receptor, R2 subunit, GABA-B-R2, GABA-BR2, gamma-aminobutyric acid (GABA) B receptor, 2, gamma-aminobutyric acid B receptor 2, gb2
- Genomic Location:
- Chr 9: 100090187-100511300
- Description:
-
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This recepto...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
9q22.33
GO Molecular Function
neurotransmitter receptor activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity | protein heterodimerization activity | GABA receptor activity | protein binding | protein dimerization activity | G-protein coupled GABA receptor activity
GO Biological Process
cellular process | gamma-aminobutyric acid signaling pathway | chemical synaptic transmission | regulation of cellular process | G-protein coupled receptor activity | negative regulation of lyase activity | response to stimulus | G-protein coupled receptor signaling pathway | cell-cell signaling | negative regulation of catalytic activity | regulation of catalytic activity | synaptic signaling | negative regulation of adenylate cyclase activity | regulation of cyclase activity | cell communication | G-protein coupled GABA receptor activity | regulation of adenylate cyclase activity | negative regulation of molecular function | signaling | signal transduction
GO Cellular Component
integral component of membrane | synapse | neuron projection | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | G-protein coupled receptor complex | cytoplasm | G-protein coupled receptor heterodimeric complex | receptor complex | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | GABA receptor complex | integral component of plasma membrane | cell periphery | G-protein coupled receptor dimeric complex | intracellular | cell junction | membrane | intrinsic component of plasma membrane
