QuickView for GABARAP (gene)

Gene Symbol:

GABARAP Homo sapiens

Full name:

GABA type A receptor-associated protein

Synonyms:

ATG8A, GABARAP-a, MM46, gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein

Genomic Location:

Chr 17: 7084462-7086477

Description:

Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein...

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Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SP1_01 ,  USF_Q6 ,  TCANNTGAY_SREBP1_01 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  CIZ_01 ,  GGCACAT_MIR455 ,  FAC1_01 ,  CTTTGA_LEF1_Q2 ,  PBX1_01 ,  GGGAGGRR_MAZ_Q6 ,  LFA1_Q6 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  USF_C ,  GCGNNANTTCC_UNKNOWN ,  IRF_Q6 ,  USF_01 ,  GFI1_01 ,  TTGTTT_FOXO4_01 ,  CP2_02 ,  GTGGGTGK_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  AAACCAC_MIR140 ,  AACTTT_UNKNOWN ,  ACAWYAAAG_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  USF_02 ,  CTGRYYYNATT_UNKNOWN ,  SP1_Q2_01 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-542-3p ,  Predicted Gene Targets for miR-140 ,  Predicted Gene Targets for miR-455

Cytogenetic Map:

17p13.1

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