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QuickView for GABRA6 (gene)


Gene Symbol:
GABRA6 Homo sapiens Homo sapiens
Full name:
gamma-aminobutyric acid type A receptor alpha6 subunit
Synonyms:
gamma-aminobutyric acid receptor subunit alpha-6, GABA subunit A receptor alpha 6, GABA(A) receptor subunit alpha-6, GABA(A) receptor, alpha 6, gamma-aminobutyric acid (GABA) A receptor, alpha 6
Genomic Location:
Chr 5: 161045236-161062176
Description:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5
5q34


Transcripts Names
NM_000811
Protein Names
Q4VAV2
Q16445
A8K096



GO Molecular Function

transmitter-gated ion channel activity | neurotransmitter receptor activity | anion transmembrane transporter activity | benzodiazepine receptor activity | GABA-A receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | chloride channel activity | inorganic anion transmembrane transporter activity | GABA-gated chloride ion channel activity | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | chloride transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | GABA receptor activity | anion channel activity | channel activity | inhibitory extracellular ligand-gated ion channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | establishment of localization | anion transmembrane transporter activity | cellular process | gamma-aminobutyric acid signaling pathway | localization | passive transmembrane transporter activity | chemical synaptic transmission | anion transport | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | chloride transmembrane transport | response to stimulus | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | chloride channel activity | chloride transport | inorganic anion transport | G-protein coupled receptor signaling pathway | inorganic anion transmembrane transporter activity | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | GABA-gated chloride ion channel activity | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | chloride transmembrane transporter activity | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | cell communication | anion transmembrane transport | cell surface receptor signaling pathway | anion channel activity | transmembrane transport | signaling | channel activity | synaptic transmission, GABAergic | inhibitory extracellular ligand-gated ion channel activity | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | cell projection membrane | cell | intrinsic component of membrane | synaptic membrane | receptor complex | dendritic tree | leading edge membrane | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | GABA receptor complex | cell leading edge | chloride channel complex | integral component of plasma membrane | dendrite membrane | cell periphery | transmembrane transporter complex | ion channel complex | cell junction | membrane | neuron projection membrane | GABA-A receptor complex | intrinsic component of plasma membrane