QuickView for GABRG2 (gene)

Gene Symbol:

GABRG2 Homo sapiens

Full name:

gamma-aminobutyric acid type A receptor gamma2 subunit

Synonyms:

CAE2, ECA2, GEFSP3, gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, GABA(A) receptor, gamma 2, gamma-aminobutyric acid (GABA) A receptor, gamma 2

Genomic Location:

Chr 5: 161427295-161515106

Description:

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene...

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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_03 ,  ZIC1_01 ,  OCT1_04 ,  MEIS1BHOXA9_01 ,  ATGTACA_MIR493 ,  ZIC3_01 ,  CTTTGA_LEF1_Q2 ,  TGACCTY_ERR1_Q2 ,  WHN_B ,  NRSF_01 ,  GGGAGGRR_MAZ_Q6 ,  LEF1_Q6 ,  TTGGGAG_MIR150 ,  LFA1_Q6 ,  CAGGTG_E12_Q6 ,  EGR_Q6 ,  ATGCTGC_MIR103_MIR107 ,  CAGNWMCNNNGAC_UNKNOWN ,  E47_01 ,  PAX8_B ,  OCT1_02 ,  POU3F2_02 ,  TTGTTT_FOXO4_01 ,  ATF1_Q6 ,  RTTTNNNYTGGM_UNKNOWN ,  ZIC2_01 ,  CTTTGT_LEF1_Q2 ,  ER_Q6_02 ,  YNGTTNNNATT_UNKNOWN ,  PPAR_DR1_Q2 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-150 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-496

Cytogenetic Map:

5q34

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