QuickView for GADD45B (gene)
- Gene Symbol:
- GADD45B
Homo sapiens - Full name:
- growth arrest and DNA damage inducible beta
- Synonyms:
- GADD45BETA, MYD118, growth arrest and DNA damage-inducible protein GADD45 beta, myeloid differentiation primary response protein MyD118, negative growth regulatory protein MyD118
- Genomic Location:
- Chr 19: 2427135-2429257
- Description:
-
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEK...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Danio rerio , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
19p13.3
GO Molecular Function
GO Biological Process
negative regulation of phosphorylation | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | cell differentiation | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | cellular process | positive regulation of protein kinase activity | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of cellular protein metabolic process | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | positive regulation of protein metabolic process | response to stress | negative regulation of protein kinase activity | activation of MAPKKK activity | programmed cell death | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | activation of protein kinase activity | regulation of cellular response to stress | apoptotic process | regulation of signal transduction | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | regulation of MAPK cascade | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of p38MAPK cascade | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | activation of MAPKK activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | positive regulation of molecular function | positive regulation of protein modification process | regulation of kinase activity | regulation of intracellular signal transduction | anatomical structure development | positive regulation of cell death | cell death | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of JNK cascade | positive regulation of MAPK cascade | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of molecular function | positive regulation of phosphorylation | positive regulation of MAP kinase activity | developmental process | positive regulation of metabolic process | regulation of cell death | positive regulation of signaling | regulation of signaling | regulation of p38MAPK cascade | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
