QuickView for GATA2 (gene)

Gene Symbol:

GATA2 Homo sapiens

Full name:

GATA binding protein 2

Synonyms:

DCML, IMD21, MONOMAC, NFE1B, endothelial transcription factor GATA-2

Genomic Location:

Chr 3: 129680960-129694718

Description:

This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell ...

View Full Description

This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  SMTTTTGT_UNKNOWN ,  GCANCTGNY_MYOD_Q6 ,  WGTTNNNNNAAA_UNKNOWN ,  ACTGTGA_MIR27A_MIR27B ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  WTGAAAT_UNKNOWN ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  MYOD_Q6 ,  AP2_Q6 ,  TTGTTT_FOXO4_01 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  AGGGCAG_MIR18A ,  CTTTGT_LEF1_Q2 ,  SRY_02 ,  LMO2COM_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

3q21.3

search → result