QuickView for GCA (gene)

Gene Symbol:

GCA Homo sapiens

Full name:

grancalcin

Synonyms:

GCL, grancalcin, grancalcin, EF-hand calcium-binding protein, grancalcin, penta-EF-hand protein

Genomic Location:

Chr 2: 162908896-162925875

Description:

This gene encodes a calcium-binding protein that is abundant in neutrophils and macrophages. In the absence of divalent cation, this protein localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions. Alt...

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This gene encodes a calcium-binding protein that is abundant in neutrophils and macrophages. In the absence of divalent cation, this protein localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions. Alternative splicing and use of alternative promoters results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  NFY_C ,  NFY_Q6_01 ,  CAGGTG_E12_Q6 ,  NFY_Q6

Cytogenetic Map:

2q24.2

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